Literature DB >> 4282387

Analysis of glutamate decarboxylase in post-mortem brain tissue in Huntington's chorea.

L L Iversen, E D Bird, A V Mackay, C N Rayner.   

Abstract

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Year:  1974        PMID： 4282387     DOI： 10.1016/0022-3956(74)90099-5

Source DB:  PubMed          Journal:  J Psychiatr Res        ISSN： 0022-3956            Impact factor:   4.791


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  6 in total

1.  The 2011 E. B. Hershberg award for important discoveries in medicinally active substances: (1S,3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a GABA aminotransferase inactivator and new treatment for drug addiction and infantile spasms.

Authors:  Richard B Silverman
Journal:  J Med Chem       Date:  2012-01-10       Impact factor: 7.446

2.  Design and mechanism of tetrahydrothiophene-based γ-aminobutyric acid aminotransferase inactivators.

Authors:  Hoang V Le; Dustin D Hawker; Rui Wu; Emma Doud; Julia Widom; Ruslan Sanishvili; Dali Liu; Neil L Kelleher; Richard B Silverman
Journal:  J Am Chem Soc       Date:  2015-03-30       Impact factor: 15.419

3.  Fluorinated conformationally restricted gamma-aminobutyric acid aminotransferase inhibitors.

Authors:  Hejun Lu; Richard B Silverman
Journal:  J Med Chem       Date:  2006-12-14       Impact factor: 7.446

4.  Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid.

Authors:  Hyunbeom Lee; Hoang V Le; Rui Wu; Emma Doud; Ruslan Sanishvili; John F Kellie; Phillip D Compton; Boobalan Pachaiyappan; Dali Liu; Neil L Kelleher; Richard B Silverman
Journal:  ACS Chem Biol       Date:  2015-07-06       Impact factor: 5.100

5.  Platelet monoamine oxidase activity in Huntington's chorea.

Authors:  J Mann; E Chiu
Journal:  J Neurol Neurosurg Psychiatry       Date:  1978-09       Impact factor: 10.154

6.  Design and Mechanism of (S)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent γ-Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Addiction.

Authors:  Jose I Juncosa; Kenji Takaya; Hoang V Le; Matthew J Moschitto; Pathum M Weerawarna; Romila Mascarenhas; Dali Liu; Stephen L Dewey; Richard B Silverman
Journal:  J Am Chem Soc       Date:  2018-01-30       Impact factor: 15.419
  6 in total

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