| Literature DB >> 4281775 |
Abstract
The inactivation of Neurospora crassa conidia by galactosaminoglycan isolated from cultures of this organism was followed by measuring colony-forming ability and ability to take up radiolabeled metabolites. When kinetic data on the loss of transport function and on killing were analyzed by use of target theory, it appeared that few "hits" are required for inactivation. However, studies with radio-labeled galactosaminoglycan mucopolysaccharides showed that cells receiving a single lethal hit have approximately 10(5) galactosaminoglycan molecules bound to them.Entities:
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Year: 1974 PMID: 4281775 PMCID: PMC245836 DOI: 10.1128/jb.120.2.759-766.1974
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490