Literature DB >> 4280069

A pyruvate-valine enzyme complex that is dependent upon the metabolic state of the mitochondria.

A Bergquist, E A Eakin, D K Murali, R P Wagner.   

Abstract

Data are presented suggesting that intact Neurospora crassa mitochondria contain an enzyme complex incorporating five enzymes necessary for the biosynthesis of isoleucine and valine. The functional integrity and stability of the complex has been shown to be dependent on the metabolic state of the mitochondria. The complex has been solubilized by digitonin and has an approximate molecular weight of 400,000.

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Year:  1974        PMID: 4280069      PMCID: PMC433881          DOI: 10.1073/pnas.71.11.4352

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  10 in total

1.  Molecular weight determination by chromatography on sepharose 4B.

Authors:  J Marrink; M Gruber
Journal:  FEBS Lett       Date:  1969-02       Impact factor: 4.124

2.  Synthesis of valine and isoleucine in the presence of a particulate cell fraction of Neurospora.

Authors:  R P WAGNER; A BERGQUIST
Journal:  Proc Natl Acad Sci U S A       Date:  1963-06       Impact factor: 11.205

3.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

4.  The pyruvate dehydrogenase complex from the mitochondrial fraction of Neurospora crassa.

Authors:  R W Harding; D F Caroline; R P Wagner
Journal:  Arch Biochem Biophys       Date:  1970-06       Impact factor: 4.013

5.  Growth, respiratory, and cytochrome characteristics of certain of the isoleucine-valine mutants of Neurospora crassa.

Authors:  A Bergquist; E A Eakin; R T Eakin; R P Wagner
Journal:  Biochem Genet       Date:  1974-07       Impact factor: 1.890

6.  Branded chain amino acid aminotransferases of Neurospora crassa.

Authors:  M Collins; R P Wagner
Journal:  Arch Biochem Biophys       Date:  1973-03       Impact factor: 4.013

7.  In vitro mitochondrial complementation in Neurospora crassa.

Authors:  E H Leiter; D A LaBrie; A Bergquist; R P Wagner
Journal:  Biochem Genet       Date:  1971-12       Impact factor: 1.890

8.  Amino acid synthesis by the mitochondria of Neurospora crassa. I. Dependence on respiration of mitochondria.

Authors:  A Bergquist; D A LaBrie; R P Wagner
Journal:  Arch Biochem Biophys       Date:  1969-11       Impact factor: 4.013

9.  Purification and properties of dihydroxy acid dehydratase from soluble and mitochondrial fractions of Neurospora crassa.

Authors:  D H Altmiller; R P Wagner
Journal:  Arch Biochem Biophys       Date:  1970-05       Impact factor: 4.013

10.  Acetohydroxy acid synthetase with a pH optimum of 7.5 from Neurospora crassa mitochondria: characterization and partial purification.

Authors:  L Glatzer; E Eakin; R P Wagner
Journal:  J Bacteriol       Date:  1972-10       Impact factor: 3.490

  10 in total
  4 in total

1.  Characterization of enzymes of the branched-chain amino acid biosynthetic pathway in Methanococcus spp.

Authors:  R Y Xing; W B Whitman
Journal:  J Bacteriol       Date:  1991-03       Impact factor: 3.490

2.  Imidazolinones and acetohydroxyacid synthase from higher plants: properties of the enzyme from maize suspension culture cells and evidence for the binding of imazapyr to acetohydroxyacid synthase in vivo.

Authors:  M J Muhitch; D L Shaner; M A Stidham
Journal:  Plant Physiol       Date:  1987-02       Impact factor: 8.340

3.  Branched-chain amino acid biosynthesis in Salmonella typhimurium: a quantitative analysis.

Authors:  S Epelbaum; R A LaRossa; T K VanDyk; T Elkayam; D M Chipman; Z Barak
Journal:  J Bacteriol       Date:  1998-08       Impact factor: 3.490

4.  Mutations in genes cpxA and cpxB of Escherichia coli K-12 cause a defect in isoleucine and valine syntheses.

Authors:  J McEwen; P Silverman
Journal:  J Bacteriol       Date:  1980-10       Impact factor: 3.490

  4 in total

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