Literature DB >> 4277750

Uncoupling activity of the anthelmintic oxyclozanide in rodents.

G H Veenendaal, M J de Waal.   

Abstract

The uncoupling activity of oxyclozanide in warm blooded animals has been studied in whole animals, isolated tissue in vitro and on mitochondrial preparations. The onset of post mortem rigidity in mice and rats is accelerated and a contracture of striated muscle is produced. Oxyclozanide (1 muM) stimulated rat liver mitochondrial respiration and stimulated an ATP-ase activity.

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Year:  1974        PMID： 4277750      PMCID： PMC1776682          DOI： 10.1111/j.1476-5381.1974.tb09622.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  9 in total

1.  [Experimental studies on N-(2'-chloro-4'-nitrophenyl)-5-chlorosalicylamide, a new teniacide. I. Chemotherapeutic experiments].

Authors:  R GOENNERT; E SCHRAUFSTAETTER
Journal:  Arzneimittelforschung       Date:  1960-11

2.  The behaviour of mammalian striated muscle in the presence of 2:4-dinitrophenol.

Authors:  J M BARNES; J I DUFF; C J THRELFALL
Journal:  J Physiol       Date:  1955-12-29       Impact factor: 5.182

3.  The enzymic hydrolysis of adenosine triphosphate by liver mitochondria. I. Activities at different pH values.

Authors:  D K MYERS; E C SLATER
Journal:  Biochem J       Date:  1957-12       Impact factor: 3.857

4.  Respiratory granules of heart muscle.

Authors:  K W CLELAND; E C SLATER
Journal:  Biochem J       Date:  1953-03       Impact factor: 3.857

5.  Anthelmintics, used for the treatment of fascioliasis as uncouplers of oxidative phosphorylation in warm blooded animals.

Authors:  A S van Miert; H W Groeneveld
Journal:  Eur J Pharmacol       Date:  1969-12       Impact factor: 4.432

6.  Standardised chemotherapeutical tests for immature and mature Fasciola hepatica infections in sheep.

Authors:  J C Boray; F A Happich
Journal:  Aust Vet J       Date:  1968-02       Impact factor: 1.281

7.  Chemotherapeutical tests for heavy immature Fasciola hepatica infections in sheep.

Authors:  J C Boray; F A Happich; W O Jones
Journal:  Aust Vet J       Date:  1969-03       Impact factor: 1.281

8.  Some aspects of the pathogenesis and treatment of fascioliasis.

Authors:  K B Sinclair
Journal:  Vet Rec       Date:  1969-05-31       Impact factor: 2.695

9.  A METHOD FOR THE COLORIMETRIC DETERMINATION OF PHOSPHORUS.

Authors:  J B Sumner
Journal:  Science       Date:  1944-11-03       Impact factor: 47.728
  9 in total
  3 in total

1.  The effect of the hydrogen ionophore closantel upon the pharmacology and ultrastructure of the adult liver fluke Fasciola hepatica.

Authors:  P J Skuce; I Fairweather
Journal:  Parasitol Res       Date:  1990       Impact factor: 2.289

2.  Comparative pharmacokinetics of levamisole-oxyclozanide combination in sheep and goats following per os administration.

Authors:  Cengiz Gokbulut; Hande Sultan Yalinkilinc; Dilek Aksit; Vincenzo Veneziano
Journal:  Can J Vet Res       Date:  2014-10       Impact factor: 1.310

3.  Determination of Oxyclozanide in Beef and Milk using High-Performance Liquid Chromatography System with UV Detector.

Authors:  Kyul Jo; Hee-Jung Cho; Hee Yi; Soo-Min Cho; Jin-A Park; Chan-Hyeok Kwon; Hee-Ra Park; Ki-Sung Kwon; Ho-Chul Shin
Journal:  Lab Anim Res       Date:  2011-03-25
  3 in total

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