Experimental edema disease of swine (E. coli enterotoxemia). II. The development of hypertension after the intravenous administration of edema disease principle.

The intravenous inoculation of edema disease principle induced profound hypertension in pigs. The increase in blood pressure occurred approximately 40 hours after inoculation and coincided with the development of the characteristic neurological disturbance of edema disease. Therefore hypertension may play a pathogenetic role in the neuropathy of experimental edema disease.