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Literature DB >> 4272505

Treatment of gonorrheal urethritis with spectinomycin hydrochloride.

J Brown, O Tabert, J D Hanna, P L Rentiers.

Abstract

One hundred and eighty-seven males with uncomplicated gonorrheal urethritis were treated with spectinomycin hydrochloride in a dosage of 2 g. given intramuscularly. A failure rate of 3.2% was observed and no complications of therapy were encountered. In addition, 310 strains of N. gonorrhoeae were tested for susceptibility to penicillin G and spectinomycin. All strains were sensitive to 20 mug./ml. of spectinomycin and this susceptibility appeared to decrease as penicillin resistance increased. A greater incidence of relative resistance to penicillin G was observed than in similar studies from other Canadian areas.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1974 PMID： 4272505 PMCID： PMC1947120

Source DB: PubMed Journal: Can Med Assoc J ISSN： 0008-4409 Impact factor: 8.262

17 in total

1. "Trobicin hydrochloride" in the treatment of gonorrhoea.

Authors: W M Platts
Journal: Med J Aust Date: 1970-09-12 Impact factor: 7.738

2. Spectinomycin hydrochloride in the treatment of uncomplicated gonorrhoea.

Authors: C E Cornelius; G Domescik
Journal: Br J Vener Dis Date: 1970-06

3. A modified formula for the preparation of Stuart's Transport Medium.

Authors: C R Amies
Journal: Can J Public Health Date: 1967-07

4. Single oral dose ampicillin-probenecid treatment of gnorrhea in the male.

Authors: P A Kvale; T F Keys; D W Johnson; K K Holmes
Journal: JAMA Date: 1971-03-01 Impact factor: 56.272

5. Therapy for incubating syphilis. Effectiveness of gonorrhea treatment.

Authors: A L Schroeter; R H Turner; J B Lucas; W J Brown
Journal: JAMA Date: 1971-11-01 Impact factor: 56.272

6. Treatment of gonorrhea. Penicillin or tetracyclines?

Authors: H H Neumann; J M Baecker
Journal: JAMA Date: 1972-01-24 Impact factor: 56.272

Review 7. Gonorrhea.

Authors: A L Schroeter; G J Pazin
Journal: Ann Intern Med Date: 1970-04 Impact factor: 25.391

8. Sensitivity of Neisseria gonorrhoeae to penicillin and other antibiotics. Studies carried out in Toronto during the period 1961 to 1968.

Authors: C R Amies
Journal: Br J Vener Dis Date: 1969-09