Literature DB >> 4263508

Activation of membrane-bound adenylate cyclase by glucagon in Neurospora crassa.

M M Flawiá, H N Torres.   

Abstract

Membrane-bound adenylate cyclase in Neurospora crassa is activated by glucagon. Half-maximal effect is observed at hormone concentrations of about 10 nM. After solubilization of the enzyme with Lubrol-PX, the glucagon effect is lost. Incubation of neurospora cells with glucagon leads to a decrease in the activity of glycogen synthetase (EC 2.4.1.11) and to an increase in the activity of glycogen phosphorylase (EC 2.4.1.1) and in the rate of glycogenolysis.

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Year:  1972        PMID： 4263508      PMCID： PMC389664          DOI： 10.1073/pnas.69.10.2870

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  15 in total

1.  Metabolism of isolated fat cells. V. Preparation of "ghosts" and their properties; adenyl cyclase and other enzymes.

Authors:  M Rodbell
Journal:  J Biol Chem       Date:  1967-12-25       Impact factor: 5.157

2.  Solubilization of myocardial adenyl cyclase.

Authors:  G S Levey
Journal:  Biochem Biophys Res Commun       Date:  1970-01-06       Impact factor: 3.575

3.  A simple, sensitive method for the assay of adenyl cyclase.

Authors:  G Krishna; B Weiss; B B Brodie
Journal:  J Pharmacol Exp Ther       Date:  1968-10       Impact factor: 4.030

4.  Adenyl cyclase in plasma membrane preparations of sea urchin eggs and its increase in activity after fertilization.

Authors:  M Castañeda; A Tyler
Journal:  Biochem Biophys Res Commun       Date:  1968-12-09       Impact factor: 3.575

5.  Adenyl cyclase in fat cells. II. Hormone receptors.

Authors:  L Birnbaumer; M Rodbell
Journal:  J Biol Chem       Date:  1969-07-10       Impact factor: 5.157

6.  Interconvertible forms of glycogen synthetase in Neurospora crassa.

Authors:  M T Téllez-Iñón; H Terenzi; H N Torres
Journal:  Biochim Biophys Acta       Date:  1969

Review 7.  The role of cyclic-3',5'-AMP in responses to catecholamines and other hormones.

Authors:  E W Sutherland; G A Robison
Journal:  Pharmacol Rev       Date:  1966-03       Impact factor: 25.468

8.  Hormone action at the membrane level. II. The binding of epinephrine and glucagon to the rat liver plasma membrane.

Authors:  V Tomasi; S Koretz; T K Ray; J Dunnick; G V Marinetti
Journal:  Biochim Biophys Acta       Date:  1970-07-07

9.  The preparation of 32P-labelled nucleoside 5'-monophosphates.

Authors:  A W Greenlees; R H Symons
Journal:  Biochim Biophys Acta       Date:  1966-05-19

10.  Interconvertible forms of glycogen phosphorylase in Neurospora crassa.

Authors:  M T Téllez-Iñón; H N Torres
Journal:  Proc Natl Acad Sci U S A       Date:  1970-06       Impact factor: 11.205
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  5 in total

1.  Enzymology and genetic regulation of a cyclic nucleotide-binding phosphodiesterase-phosphomonoesterase from Aspergillus nidulans.

Authors:  G M Polya; A G Brownlee; M J Hynes
Journal:  J Bacteriol       Date:  1975-11       Impact factor: 3.490

2.  A cell-contact model for cellular position determination in development.

Authors:  D McMahon
Journal:  Proc Natl Acad Sci U S A       Date:  1973-08       Impact factor: 11.205

Review 3.  Adenosine 3',5'-phosphate in fungi.

Authors:  M L Pall
Journal:  Microbiol Rev       Date:  1981-09

4.  Cyclic nucleotide phosphodiesterase activities in Neurospora crassa.

Authors:  M T Téllez-Iñón; G C Glikin; H N Torres
Journal:  Biochem J       Date:  1982-06-01       Impact factor: 3.857

5.  Regulatory role of nucleotides, nucleosides and their deoxy derivatives on adenylate cyclase of Mycobacterium smegmatis.

Authors:  C H Lee
Journal:  Folia Microbiol (Praha)       Date:  1983       Impact factor: 2.099
  5 in total

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