Literature DB >> 4262277

Pharmacokinetics of digoxin and its 4'''-acetyl- and methylderivates in the rat.

N Rietbrock, U Abshagen, K von Bergmann, H Kewitz.   

Abstract

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Year:  1972        PMID： 4262277     DOI： 10.1007/bf00501851

Source DB:  PubMed          Journal:  Naunyn Schmiedebergs Arch Pharmacol        ISSN： 0028-1298            Impact factor:   3.000


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  16 in total

1.  [DETOXIFICATION RATE AND ACCUMULATION OF DIGITOXIN IN DIFFERENT SPECIES].

Authors:  I HERRMANN; K REPKE
Journal:  Naunyn Schmiedebergs Arch Exp Pathol Pharmakol       Date:  1964-04-09

2.  [Absorption and decomposition of glycosides with cardiac action. 2. Decomposition of cardenolide glycosides in vitro].

Authors:  K LINGNER; W KUESSNER
Journal:  Arzneimittelforschung       Date:  1962-08

3.  [Intestinal absorption of cardiac glycosides in vitro and in vivo].

Authors:  W Forth; E Furukawa; W Rummel
Journal:  Naunyn Schmiedebergs Arch Exp Pathol Pharmakol       Date:  1969

4.  [On the cause of species differences in digitalis sensitivity].

Authors:  K Repke; M Est; H J Portius
Journal:  Biochem Pharmacol       Date:  1965-12       Impact factor: 5.858

5.  Evaluation of the enterohepatic circulation after 3 H-digoxin administration in the rat.

Authors:  U Abshagen; K von Bergmann; N Rietbrock
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1972       Impact factor: 3.000

6.  -methyl-digoxin. 3. Speed of absorption in guinea-pigs in comparison to other cardiac glycosides.

Authors:  W Schaumann; F Zielske; K Kohler; K Koch
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1972       Impact factor: 3.000

7.  [Determination of the intestinal absorption of cardiac glycosides by measurement of 3H-labelled glycosides in the portal venous blood and in the intestinal lymph of cats].

Authors:  W Forth; E Furukawa; W Rummel
Journal:  Naunyn Schmiedebergs Arch Pharmakol       Date:  1969

8.  [Intestinal secretion of cardiotonic steroids--studies on the mechanism of the absorption process].

Authors:  F Lauterbach
Journal:  Naunyn Schmiedebergs Arch Pharmakol       Date:  1969

9.  Comparison of intestinal penetration of cortisol and convallatoxin: demonstration of a transport mechanism for cardiotonic steroids.

Authors:  F Lauterbach
Journal:  Biochim Biophys Acta       Date:  1968-01-03

10.  [Partly synthetic cardiac glycoside derivatives with improved enteral effectiveness. 28. Cardiac glycosides].

Authors:  F Kaiser
Journal:  Planta Med       Date:  1971       Impact factor: 3.352
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  13 in total

1.  Modification of the P-glycoprotein dependent pharmacokinetics of digoxin in rats by human recombinant interferon-alpha.

Authors:  Makrem Ben Reguiga; Laurence Bonhomme-Faivre; Simone Orbach-Arbouys; Robert Farinotti
Journal:  Pharm Res       Date:  2005-08-16       Impact factor: 4.200

2.  Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein.

Authors:  U Mayer; E Wagenaar; J H Beijnen; J W Smit; D K Meijer; J van Asperen; P Borst; A H Schinkel
Journal:  Br J Pharmacol       Date:  1996-11       Impact factor: 8.739

3.  Beta-methyl-digoxin. VI. Tissue distribution and therapeutic ratio in guinea pigs in comparison with digoxin.

Authors:  W Schaumann; K Koch
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1974       Impact factor: 3.000

4.  Beta-methyl-digoxin. V. Protein binding, tissue distribution and extra-cardiac effects in rats and mice.

Authors:  A Roesch; K Koch; W Schaumann
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1973       Impact factor: 3.000

5.  Effects of pretreatment with spironolactone on pharmacokinetics of 4'''-methyldigoxin in rats.

Authors:  U Abshagen
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1973       Impact factor: 3.000

6.  Evaluation of the enterohepatic circulation after 3 H-digoxin administration in the rat.

Authors:  U Abshagen; K von Bergmann; N Rietbrock
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1972       Impact factor: 3.000

7.  Beta-methyl-digoxin. VII. Tissue distribution, positive inotropic and central action in cats in comparison with other digitalis glycosides.

Authors:  W Schaumann; K Koch
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1974       Impact factor: 3.000

8.  Hepatic clearance of gitoxin: pharmacokinetic study on rabbit isolated liver. Influence of protein binding and comparison with digoxin.

Authors:  P Pellegrin; M Lesne
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1983       Impact factor: 2.441

9.  Absorption of digoxin in man after oral and intrasigmoid administration studied by portal vein catheterization.

Authors:  K E Andersson; L Nyberg; H Dencker; J Göthlin
Journal:  Eur J Clin Pharmacol       Date:  1975-10-10       Impact factor: 2.953

10.  Cleavage of digoxigenin digitoxosides by rat liver microsomes.

Authors:  A Schmoldt; B Ahsendorf
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1980       Impact factor: 2.441
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