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Literature DB >> 4261830

Experimental papillary necrosis of the kidney. II. Electron microscopic and histochemical studies.

G S Hill, R G Wyllie, M Miller, R R Heptinstall.

Abstract

Renal papillary necrosis was induced in rats by bromoethylamine hydrobromide and studied electron microscopically and histochemically. Morphologic changes appear to develop in vessels and tubules simultaneously, rather than tubular lesions preceding and leading to vascular lesions, or vice versa. Abnormalities are recognized as early as 3 hours, but platelets do not make their appearance until 12 hours, eliminating primary vascular thrombosis as the source of papillary injury.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1972 PMID： 4261830 PMCID： PMC2032687

Source DB: PubMed Journal: Am J Pathol ISSN： 0002-9440 Impact factor: 4.307

21 in total

1. Human renal ultrastructure. II. The thin limb of Henle's loop and the interstitium in healthy individuals.

Authors: R E Bulger; C C Tisher; C H Myers; B F Trump
Journal: Lab Invest Date: 1967-01 Impact factor: 5.662

2. Acute renal failure in the rat. II. Light and electron microscopic observations.

Authors: S Rosen; L U Mailloux; N L Lawson; P E Teschan
Journal: Lab Invest Date: 1968-04 Impact factor: 5.662

3. Studies of cellular injury in isolated flounder tubules. I. Correlation between morphology and function of control tubules and observations of autophagocytosis and mechanical cell damage.

Authors: B F Trump; R E Bulger
Journal: Lab Invest Date: 1967-03 Impact factor: 5.662

4. The influence of different fixatives and fixation methods on the ultrastructure of rat kidney proximal tubule cells. II. Effects of varying osmolality, ionic strength, buffer system and fixative concentration of glutaraldehyde solutions.

Authors: A B Maunsbach
Journal: J Ultrastruct Res Date: 1966-06

5. Fine structure of the rat renal papilla.

Authors: R E Bulger; B F Trump
Journal: Am J Anat Date: 1966-05

6. Interstitial cells of the renal medulla.

Authors: L Osvaldo; H Latta
Journal: J Ultrastruct Res Date: 1966-08

7. The thin limbs of the loop of Henle.

Authors: L Osvaldo; H Latta
Journal: J Ultrastruct Res Date: 1966-04

8. The fine structure of the blood vessels of the renal medulla with particular reference to the control of the medullary circulation.

Authors: D B Moffat
Journal: J Ultrastruct Res Date: 1967-08-30

9. Studies on the pathogenesis of serum-induced renal papillary necrosis in the rat. 3. The early morphologic changes studied by light and electron microscopy.

Authors: A Ljungqvist; L Osvaldo-Decima; J Richardson
Journal: Lab Invest Date: 1967-10 Impact factor: 5.662

Experimental papillary necrosis of the kidney. II. Electron microscopic and histochemical studies.

1. Human renal ultrastructure. II. The thin limb of Henle's loop and the interstitium in healthy individuals.

2. Acute renal failure in the rat. II. Light and electron microscopic observations.

3. Studies of cellular injury in isolated flounder tubules. I. Correlation between morphology and function of control tubules and observations of autophagocytosis and mechanical cell damage.

4. The influence of different fixatives and fixation methods on the ultrastructure of rat kidney proximal tubule cells. II. Effects of varying osmolality, ionic strength, buffer system and fixative concentration of glutaraldehyde solutions.

5. Fine structure of the rat renal papilla.

6. Interstitial cells of the renal medulla.

7. The thin limbs of the loop of Henle.

8. The fine structure of the blood vessels of the renal medulla with particular reference to the control of the medullary circulation.

9. Studies on the pathogenesis of serum-induced renal papillary necrosis in the rat. 3. The early morphologic changes studied by light and electron microscopy.

10. Early morphologic changes in serum-induced renal papillary necrosis. Light and electron microscopic studies.

1. The effects of chronic papillary necrosis on acid excretion.

2. Variability in the renal clearance of cephalexin in experimental renal failure.

3. Prediction of the renal clearance of cimetidine using endogenous N-1-methylnicotinamide.

4. Experimental papillary necrosis of the kidney. IV. Medullary plasma flow.