Literature DB >> 4260501

Hepatic and extrahepatic metabolism of the psychotropic drugs, chlorpromazine, imipramine, and imipramine-N-oxide.

R Minder, F Schnetzer, M H Bickel.   

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Year:  1971        PMID: 4260501     DOI: 10.1007/bf00997266

Source DB:  PubMed          Journal:  Naunyn Schmiedebergs Arch Pharmakol


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  16 in total

1.  Metabolism of chlorpromazine: organic-extractable fraction from human urine.

Authors:  V FISHMAN; H GOLDENBERG
Journal:  Proc Soc Exp Biol Med       Date:  1960-05

2.  Biochemical and pharmacological changes in the rat following chronic administration of morphine nalorphine and normorphine.

Authors:  J COCHIN; J AXELROD
Journal:  J Pharmacol Exp Ther       Date:  1959-02       Impact factor: 4.030

3.  The colorimetric estimation of formaldehyde by means of the Hantzsch reaction.

Authors:  T NASH
Journal:  Biochem J       Date:  1953-10       Impact factor: 3.857

4.  Model metabolites of chlorpromazine and promazine: relative activities in some pharmacological and behavioral tests.

Authors:  H S POSNER; E HEARST; W L TAYLOR; G J COSMIDES
Journal:  J Pharmacol Exp Ther       Date:  1962-07       Impact factor: 4.030

5.  Application of isotope derivative technique to assay of secondary amines: estimation of desipramine by acetylation with H3-acetic anhydride.

Authors:  W M Hammer; B B Brodiet
Journal:  J Pharmacol Exp Ther       Date:  1967-09       Impact factor: 4.030

6.  Biotransformations in vitro undergone by phenothiazine derivatives in a liver preparation.

Authors:  A E Robinson
Journal:  J Pharm Pharmacol       Date:  1966-01       Impact factor: 3.765

7.  The total fate of a drug: kinetics of distribution, excretion, and formation of 14 metabolites in rats treated with imipramine.

Authors:  M H Bickel; H J Weder
Journal:  Arch Int Pharmacodyn Ther       Date:  1968-06

8.  Metabolic interconversions between imipramine, its N-oxide, and its desmethyl derivative in rat tissues in vitro.

Authors:  M H Bickel; H J Weder; H Aebi
Journal:  Biochem Biophys Res Commun       Date:  1968-12-30       Impact factor: 3.575

9.  The metabolism of chlorpromazine by liver microsomal enzyme systems.

Authors:  P F Coccia; W W Westerfeld
Journal:  J Pharmacol Exp Ther       Date:  1967-08       Impact factor: 4.030

10.  SPECIES DIFFERENCES IN THE METABOLISM OF IMIPRAMINE AND DESMETHYLIMIPRAMINE (DMI).

Authors:  J V DINGELL; F SULSER; J R GILLETTE
Journal:  J Pharmacol Exp Ther       Date:  1964-01       Impact factor: 4.030

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  12 in total

1.  The metabolism of dothiepin hydrochloride in vivo and in vitro [proceedings].

Authors:  E L Crampton; W Dickinson; G Haran; B Marchant; P C Risdall; P A Berry
Journal:  Br J Pharmacol       Date:  1978-11       Impact factor: 8.739

Review 2.  Formation of active metabolites of psychotropic drugs. An updated review of their significance.

Authors:  S Caccia; S Garattini
Journal:  Clin Pharmacokinet       Date:  1990-06       Impact factor: 6.447

3.  Uptake, subcellular distribution, and transfer processes of imipramine and its metabolites formed in rat liver perfusion systems.

Authors:  M H Bickel; H Börner
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1974       Impact factor: 3.000

4.  Metabolism of hydrazines and hydrazides by the intestinal microflora.

Authors:  G C Bolton; L A Griffiths
Journal:  Experientia       Date:  1978-11-15

5.  Clinical pharmacokinetic studies of perphenazine.

Authors:  C Eggert Hansen; T Rosted Christensen; J Elley; L Bolvig Hansen; P Kragh-Sorensen; N E Larsen; J Naestoft; E F Hvidberg
Journal:  Br J Clin Pharmacol       Date:  1976-10       Impact factor: 4.335

6.  Phase I metabolism of imipramine by microsomes of small intestine in comparison with metabolism by liver microsomes.

Authors:  W Christ; W Hecker; H Junge; G Stille
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1983-06       Impact factor: 3.000

7.  Amitriptyline pharmacokinetics. Single doses of Lentizol compared with ordinary amitriptyline tablets.

Authors:  J E Burch; R P Hullin
Journal:  Psychopharmacology (Berl)       Date:  1981       Impact factor: 4.530

8.  Amitriptyline pharmacokinetics. A crossover study with single doses of amitriptyline and nortriptyline.

Authors:  J E Burch; R P Hullin
Journal:  Psychopharmacology (Berl)       Date:  1981       Impact factor: 4.530

9.  Incorporation of chlorpromazine into bilayer liposomes for protection against microsomal metabolism and liver absorption.

Authors:  R A Schwendener
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1988 Apr-Jun       Impact factor: 2.441

10.  Formation of chlorpromazine sulphoxide and monodesmethylchlorpromazine by microsomes of small intestine.

Authors:  R Knoll; W Christ; B Müller-Oerlinghausen; H Coper
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977-03       Impact factor: 3.000

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