Literature DB >> 42555

Increased release of tumour cells by collagenase at acid pH: a possible mechanism for metastasis.

G A Turner.   

Abstract

The ability of collagenase to disaggregate a solid metastasizing lymphosarcoma has been shown to considerably increase with reducing environmental pH. It is suggested that this effect may be operating in vivo to release cells from a primary tumour.

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Year:  1979        PMID： 42555     DOI： 10.1007/bf01953252

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  4 in total

1.  Purification and partial characterization of collagenolytic enzymes from Clostridium histolyticum.

Authors:  T Kono
Journal:  Biochemistry       Date:  1968-03       Impact factor: 3.162

2.  Modifications of the acid-base status of the internal milieu of tumors.

Authors:  P M Gullino; F H Grantham; S H Smith; A C Haggerty
Journal:  J Natl Cancer Inst       Date:  1965-06       Impact factor: 13.506

3.  Studies on homotransplantable lymphomas in hamsters. I. Histologic responses in lymphoid tissues and their relationship to metastasis.

Authors:  R L Carter; R K Gershon
Journal:  Am J Pathol       Date:  1966-10       Impact factor: 4.307

4.  Radioiodination studies of tumour cell-surface proteins after different disaggregation procedures.

Authors:  D Guy; A L Latner; G A Turner
Journal:  Br J Cancer       Date:  1977-08       Impact factor: 7.640
  4 in total
  10 in total

1.  Alterations in proteolytic activity at low pH and its association with invasion: a theoretical model.

Authors:  S D Webb; J A Sherratt; R G Fish
Journal:  Clin Exp Metastasis       Date:  1999-07       Impact factor: 5.150

2.  Simultaneous pH-sensitive and oxygen-sensitive MRI of human gliomas at 3 T using multi-echo amine proton chemical exchange saturation transfer spin-and-gradient echo echo-planar imaging (CEST-SAGE-EPI).

Authors:  Robert J Harris; Jingwen Yao; Ararat Chakhoyan; Catalina Raymond; Kevin Leu; Linda M Liau; Phioanh L Nghiemphu; Albert Lai; Noriko Salamon; Whitney B Pope; Timothy F Cloughesy; Benjamin M Ellingson
Journal:  Magn Reson Med       Date:  2018-04-06       Impact factor: 4.668

3.  Concentration-independent MRI of pH with a dendrimer-based pH-responsive nanoprobe.

Authors:  Mohammed P I Bhuiyan; Madhava P Aryal; Branislava Janic; Kishor Karki; Nadimpalli R S Varma; James R Ewing; Ali S Arbab; Meser M Ali
Journal:  Contrast Media Mol Imaging       Date:  2015-07-14       Impact factor: 3.161

4.  Association between Tumor Acidity and Hypervascularity in Human Gliomas Using pH-Weighted Amine Chemical Exchange Saturation Transfer Echo-Planar Imaging and Dynamic Susceptibility Contrast Perfusion MRI at 3T.

Authors:  Y-L Wang; J Yao; A Chakhoyan; C Raymond; N Salamon; L M Liau; P L Nghiemphu; A Lai; W B Pope; N Nguyen; M Ji; T F Cloughesy; B M Ellingson
Journal:  AJNR Am J Neuroradiol       Date:  2019-05-16       Impact factor: 3.825

5.  Bicarbonate increases tumor pH and inhibits spontaneous metastases.

Authors:  Ian F Robey; Brenda K Baggett; Nathaniel D Kirkpatrick; Denise J Roe; Julie Dosescu; Bonnie F Sloane; Arig Ibrahim Hashim; David L Morse; Natarajan Raghunand; Robert A Gatenby; Robert J Gillies
Journal:  Cancer Res       Date:  2009-03-10       Impact factor: 12.701

Review 6.  Adaptive landscapes and emergent phenotypes: why do cancers have high glycolysis?

Authors:  Robert J Gillies; Robert A Gatenby
Journal:  J Bioenerg Biomembr       Date:  2007-06       Impact factor: 2.945

Review 7.  Regulation of cancer metastasis by stress pathways.

Authors:  Keping Xie; Suyun Huang
Journal:  Clin Exp Metastasis       Date:  2003       Impact factor: 5.150

8.  Glucose starvation and acidosis: effect on experimental metastatic potential, DNA content and MTX resistance of murine tumour cells.

Authors:  O K Schlappack; A Zimmermann; R P Hill
Journal:  Br J Cancer       Date:  1991-10       Impact factor: 7.640

9.  Differences in surface expression of WGA-binding proteins of cells from a lymphosarcoma and its liver metastases.

Authors:  W S Chan; A Jackson; G A Turner
Journal:  Br J Cancer       Date:  1984-02       Impact factor: 7.640

10.  Investigating mechanisms of alkalinization for reducing primary breast tumor invasion.

Authors:  Ian F Robey; Lance A Nesbit
Journal:  Biomed Res Int       Date:  2013-07-10       Impact factor: 3.411
  10 in total

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