Literature DB >> 42552

Immunological blocking of exogenous and endogenous secretin in the dog.

L Kayasseh, K Gyr, J B Baumann, J Girard.   

Abstract

In mongrel dogs with chronic gastric and duodenal fistula the biological activity of secretin on exocrine pancreatic secretion could be blocked by preincubating the secretin injected with rabbit antisecretin antibody. In addition, the activity of endogenous secretin released by acid was markedly reduced by application of antibody. Since no such effect was observed after testmeal stimulation, secretin is most probably not released in a significant amount by the liquid meal used in this experiment.

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Year:  1979        PMID： 42552     DOI： 10.1007/bf01953214

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  7 in total

1.  Measurement of endogenous release of cholecystokinin by radioimmunoassay.

Authors:  D D Reeder; H D Becker; N J Smith; P L Rayford; J C Thompson
Journal:  Ann Surg       Date:  1973-09       Impact factor: 12.969

2.  [Radioimmunoassay for secretin].

Authors:  J Girard; J B Baumann; G van Hees; L Kayasseh; N Gyr; G A Stalder
Journal:  Schweiz Med Wochenschr       Date:  1977-04-16

3.  Effect of metiamide on basal and stimulated serum cholecystokinin levels in duodenal ulcer patients.

Authors:  R W Spence; L R Celestin; R F Harvey
Journal:  Gut       Date:  1976-11       Impact factor: 23.059

4.  Comparison of the biological potency of a new synthetic preparation of secretin with that of natural porcine secretin in the dog.

Authors:  K Gyr; L Kayasseh; W W Rittmann; J Girard; G A Stalder
Journal:  Gut       Date:  1978-05       Impact factor: 23.059

5.  Effect of somatostatin on exocrine pancreatic secretion stimulated by pancreozymin-secretin or by a test meal in the dog.

Authors:  L Kayasseh; K Gyr; G A Stalder; W W Rittmann; J Girard
Journal:  Horm Res       Date:  1978

6.  Plasma secretin concentration in man: effect of intraduodenal glucose, fat, amino acids, ethanol, HCl, or ingestion of a meal.

Authors:  J Fahrenkrug; O B Schaffalitzky de Muckadell
Journal:  Eur J Clin Invest       Date:  1977-06       Impact factor: 4.686

7.  The endogenous release of pancreatic polypeptide by acid and meal in dogs. Effect of somatostatin.

Authors:  L Kayasseh; W H Haecki; K Gyr; G A Stalder; W W Rittmann; F Halter; J Girard
Journal:  Scand J Gastroenterol       Date:  1978       Impact factor: 2.423
  7 in total

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