Literature DB >> 4247738

Prebiotic synthesis of propiolaldehyde and nicotinamide.

M J Dowler, W D Fuller, L E Orgel, R A Sanchez.   

Abstract

We have identified propiololdehyde as a product of the action of an electric discharge on mixtures of methane and water or methane, nitrogen, and water. The aldehyde reacts with cyanoacetaldehyde and ammonia (other "prebiological molecules") to yield nicotinonitrile. This substance can be hydrolyzed to nicotinamide and nicotinic acid.

Entities:  

Mesh：

Substances：

Year:  1970        PMID： 4247738     DOI： 10.1126/science.169.3952.1320

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  9 in total

1.  Self-incorporation of coenzymes by ribozymes.

Authors:  R R Breaker; G F Joyce
Journal:  J Mol Evol       Date:  1995-06       Impact factor: 2.395

2.  Prebiotic synthesis from CO atmospheres: implications for the origins of life.

Authors:  Shin Miyakawa; Hiroto Yamanashi; Kensei Kobayashi; H James Cleaves; Stanley L Miller
Journal:  Proc Natl Acad Sci U S A       Date:  2002-10-30       Impact factor: 11.205

Review 3.  Chemical evolution. Recent syntheses of bioorganic molecules.

Authors:  E Stephen-Sherwood; J Oró
Journal:  Space Life Sci       Date:  1973-01

4.  Origin of terrestrial polypeptides: a theory based on data from discharge tube experiments.

Authors:  P R Griffiths; P J Schuhmann; E R Lippincott
Journal:  Space Life Sci       Date:  1973-04

5.  The atmosphere of the primitive earth and the prebiotic synthesis of amino acids.

Authors:  S L Miller
Journal:  Orig Life       Date:  1974 Jan-Apr

6.  Prebiotic syntheses of vitamin coenzymes: I. Cysteamine and 2-mercaptoethanesulfonic acid (coenzyme M).

Authors:  S L Miller; G Schlesinger
Journal:  J Mol Evol       Date:  1993-04       Impact factor: 2.395

7.  Efficient incorporation of CoA, NAD and FAD into RNA by in vitro transcription.

Authors:  Faqing Huang
Journal:  Nucleic Acids Res       Date:  2003-02-01       Impact factor: 16.971

8.  Nitrogen heterocycles form peptide nucleic acid precursors in complex prebiotic mixtures.

Authors:  Laura E Rodriguez; Christopher H House; Karen E Smith; Melissa R Roberts; Michael P Callahan
Journal:  Sci Rep       Date:  2019-06-26       Impact factor: 4.379

Review 9.  Coenzymes and Their Role in the Evolution of Life.

Authors:  Andreas Kirschning
Journal:  Angew Chem Int Ed Engl       Date:  2020-10-23       Impact factor: 15.336
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.