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Literature DB >> 4246870

Clinical and bacteriological studies with clindamycin.

A M Geddes, F A Bridgwater, D N Williams, J Oon, G J Grimshaw.

Abstract

Fifty patients have been treated with clindamycin, a chemical analogue of lincomycin. Forty-four responded satisfactorily to treatment. Gastrointestinal side-effects were rare though five patients developed rashes. Most recently isolated staphylococci are clindamycin-sensitive.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1970 PMID： 4246870 PMCID： PMC1700701 DOI： 10.1136/bmj.2.5711.703

Source DB: PubMed Journal: Br Med J ISSN： 0007-1447

2 in total

1. Comparative studies of antibacterial activity in vitro and absorption and excretion of lincomycin and clinimycin.

Authors: R F McGehee; C B Smith; C Wilcox; M Finland
Journal: Am J Med Sci Date: 1968-11 Impact factor: 2.378

2. Drug rash with ampicillin and other penicillins.

Authors: S Shapiro; V Siskind; D Slone; G P Lewis; H Jick
Journal: Lancet Date: 1969-11-08 Impact factor: 79.321

2 in total

23 in total

Review 1. Clindamycin--efficacy and toxicity.

Authors: R I Frankel
Journal: West J Med Date: 1975-06

2. [Not Available].

Authors: P Auger; P Ricard; J Carre
Journal: Can Fam Physician Date: 1972-02 Impact factor: 3.275

3. Effect of peritoneal dialysis on serum levels of tobramycin and clindamycin.

Authors: R F Malacoff; F O Finkelstein; V T Andriole
Journal: Antimicrob Agents Chemother Date: 1975-11 Impact factor: 5.191

4. Parenteral clindamycin phosphate: pharmacology with normal and abnormal liver function and effect on nasal staphylococci.

Authors: D N Williams; K Crossley; C Hoffman; L D Sabath
Journal: Antimicrob Agents Chemother Date: 1975-02 Impact factor: 5.191

Clinical and bacteriological studies with clindamycin.

1. Comparative studies of antibacterial activity in vitro and absorption and excretion of lincomycin and clinimycin.

2. Drug rash with ampicillin and other penicillins.

Review 1. Clindamycin--efficacy and toxicity.

2. [Not Available].

3. Effect of peritoneal dialysis on serum levels of tobramycin and clindamycin.

4. Parenteral clindamycin phosphate: pharmacology with normal and abnormal liver function and effect on nasal staphylococci.

5. Lincomycin and clindamycin: their role in chemotherapy of anaerobic and microaerophilic infections.

6. A studyof the pharmacokinetics of clidamycin in normal subjects and patients with chronic renal failure.

7. Parenteral and oral clindamycin therapy in surgical infections: a preliminary report.

8. Clindamycin levels in sputum in a patient with purulent chest disease due to cystic fibrosis.

9. Efficacy of intravenous clindamycin and methicillin in gram-positive soft tissue infections.

10. HLA-B*51:01 is strongly associated with clindamycin-related cutaneous adverse drug reactions.