Literature DB >> 424456

Histopathogenesis of skin and subcutaneous injury induced by adriamycin.

D W Luedke, P S Kennedy, R L Rietschel.   

Abstract

Extravasation of Adriamycin from an intravenous needle or catheter can produce a progressive skin necrosis and deep painful ulceration. The pathological changes which result in this ulceration were studied in a rabbit model. The earliest changes include vascular obliteration and necrobiosis of collagen. At no point were inflammatory cells found to play a primary role.

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Year:  1979        PMID： 424456     DOI： 10.1097/00006534-197904000-00003

Source DB:  PubMed          Journal:  Plast Reconstr Surg        ISSN： 0032-1052            Impact factor:   4.730


  8 in total

Review 1.  Cancer chemotherapy agent-induced perivenous extravasation injuries.

Authors:  A Banerjee; T M Brotherston; B G Lamberty; R C Campbell
Journal:  Postgrad Med J       Date:  1987-01       Impact factor: 2.401

2.  Outcome of chemotherapy extravasation in a large patient series using a standardised management protocol.

Authors:  Ursula Pluschnig; Werner Haslik; Günther Bayer; Afschin Soleiman; Rupert Bartsch; Wolfgang Lamm; Günther G Steger; Christoph C Zielinski; Robert M Mader
Journal:  Support Care Cancer       Date:  2014-11-30       Impact factor: 3.603

Review 3.  Prevention and management of extravasation of cytotoxic drugs.

Authors:  G Bertelli
Journal:  Drug Saf       Date:  1995-04       Impact factor: 5.606

Review 4.  [Extravasation of cytotoxic agents].

Authors:  Elisabeth Nogler-Semenitz; Ines Mader; Patrizia Fürst-Weger; Robert Terkola; Sabine Wassertheurer; Pietro Giovanoli; Robert M Mader
Journal:  Wien Klin Wochenschr       Date:  2004-05-31       Impact factor: 1.704

5.  Protective effect of doxorubicin in vitamin C or dimethyl sulfoxide against skin ulceration in the pig.

Authors:  H Hajarizadeh; L Lebredo; R Barrie; E A Woltering
Journal:  Ann Surg Oncol       Date:  1994-09       Impact factor: 5.344

6.  Tissue distribution of epirubicin after severe extravasation in humans.

Authors:  Jakob Nedomansky; Werner Haslik; Ursula Pluschnig; Christoph Kornauth; Christine Deutschmann; Stefan Hacker; Günther G Steger; Rupert Bartsch; Robert M Mader
Journal:  Cancer Chemother Pharmacol       Date:  2021-04-27       Impact factor: 3.333

7.  The efficacy of negative pressure wound therapy on chemotherapeutic extravasation ulcers: An experimental study.

Authors:  Evren Iscı; Halil I Canter; Mehmet Dadacı; Pergin Atılla; Ayse N Cakar; Abdullah Kecık
Journal:  Indian J Plast Surg       Date:  2014 Sep-Dec

8.  A sarcoma at the site of previous extravasation of adriamycin.

Authors:  Joris Ceulemans; Ivo De Wever; Raf Sciot; Maria Debiec-Rychter; Allan T van Oosterom
Journal:  Sarcoma       Date:  2002
  8 in total

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