Literature DB >> 423715

The importance of the steric configuration of lysophosphatidylcholine in the lymphatic transport of fat.

P J O'Doherty.   

Abstract

The importance of the steric configuration of lysophosphatidylcholine in the lymphatic transport of fat was investigated in bile fistula rats. It was found that the feeding of 1-palmitoyl-sn-glycero-3-phosphocholine increased the lymphatic output of phosphatidyl choline and triacylglycerol, while the feeding of 3-palmitoyl-sn-glycero-1-phosphocholine had no effect. In intestinal microsomes of the bile fistula rats, it was found that the lysophosphatidylcholine acyltransferase was stereospecific in acylating the 1-acyl-sn-glycero-3-phosphocholine enantiomer. The significance of these findings is briefly discussed.

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Year:  1979        PMID： 423715     DOI： 10.1007/bf02533574

Source DB:  PubMed          Journal:  Lipids        ISSN： 0024-4201            Impact factor:   1.880


  14 in total

1.  Protein and glycerolipid biosynthesis in isolaged intestinal epithelial cells of normal and bile-fistula rats.

Authors:  P J O'doherty; I M Yousef; G Kakis; A Kuksis
Journal:  Arch Biochem Biophys       Date:  1975-07       Impact factor: 4.013

2.  A rapid method of total lipid extraction and purification.

Authors:  E G BLIGH; W J DYER
Journal:  Can J Biochem Physiol       Date:  1959-08

3.  Role of luminal lecithin in intestinal fat absorption.

Authors:  P J O'Doherty; G Kakis; A Kuksis
Journal:  Lipids       Date:  1973-05       Impact factor: 1.880

4.  Effect of puromycin on protein and glycerolipid biosynthesis in isolated mucosal cells.

Authors:  P J O'Doherty; I M Yousef; A Kuksis
Journal:  Arch Biochem Biophys       Date:  1973-06       Impact factor: 4.013

Review 5.  The synthesis of phosphoglycerides and some biochemical applications.

Authors:  L L van Deenen; G H de Haas
Journal:  Adv Lipid Res       Date:  1964

6.  Stimulation of CDP-choline biosynthesis by enantiomeric lysophosphatidylcholines in rat intestinal mucosa.

Authors:  P J O'Doherty; N B Smith; A Kuksis
Journal:  Arch Biochem Biophys       Date:  1977-04-15       Impact factor: 4.013

7.  Ribosome structure and chylomicron formation in rat intestinal mucosa.

Authors:  I M Yousef; P J O'Doherty; E F Whitter; A Kuksis
Journal:  Lab Invest       Date:  1976-03       Impact factor: 5.662

8.  1-Alkyl-sn-glycero-3-phosphate: acyl-CoA acyltransferase in rat brain microsomes.

Authors:  P J Fleming; A K Hajra
Journal:  J Biol Chem       Date:  1977-03-10       Impact factor: 5.157

9.  Steric requirements for the stimulation of glycosyltransferase activity by lysophosphatidylcholine.

Authors:  P J O'Doherty
Journal:  Lipids       Date:  1978-04       Impact factor: 1.880

10.  The importance of the lysophosphatidylcholine and choline moiety of bile phosphatidylcholine in lymphatic transport of fat.

Authors:  P Tso; J Lam; W J Simmonds
Journal:  Biochim Biophys Acta       Date:  1978-03-30
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  2 in total

1.  Hypolipidemic drugs are inhibitors of phosphatidylcholine synthesis.

Authors:  S Parthasarathy; D Kritchevsky; W J Baumann
Journal:  Proc Natl Acad Sci U S A       Date:  1982-11       Impact factor: 11.205

2.  Lipid absorption and metabolism.

Authors:  A Kuksis; N A Shaikh; A G Hoffman
Journal:  Environ Health Perspect       Date:  1979-12       Impact factor: 9.031
  2 in total

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