Literature DB >> 4232783

Relatively benign sickle-cell anaemia in 60 patients aged over 30 in the West Indies.

G R Serjeant, R Richards, P R Barbor, P F Milner.   

Abstract

A study in Jamaica of 60 patients with sickle-cell anaemia over the age of 30 years showed that most of them were in full-time employment. Pains in the bones or joints, leg ulceration, and jaundice were the most frequent types of presentation, but only two patients had a haemoglobin level consistently below 6 g./ 100 ml. Most of the patients were well developed and of average height, and, though the development of secondary sexual characteristics was delayed, there was an average of 2.6 pregnancies per patient. These findings suggest that the course is more benign than has been realized.

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Year:  1968        PMID: 4232783      PMCID: PMC1986086          DOI: 10.1136/bmj.3.5610.86

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  39 in total

1.  THE DIAGNOSIS OF IRON DEFICIENCY ANEMIA.

Authors:  D F BAINTON; C A FINCH
Journal:  Am J Med       Date:  1964-07       Impact factor: 4.965

2.  Improved rapid methods for the determination of iron content and binding capacity of serum.

Authors:  R N BEALE; J O BOSTROM; R F TAYLOR
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3.  The cardiogram of congenital and acquired right ventricular hypertrophy.

Authors:  J F GOODWIN; Z H ABDIN
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4.  Analysis of medical admissions to Mulago Hospital, 1957.

Authors:  A G SHAPER; L SHAPER
Journal:  East Afr Med J       Date:  1958-12

5.  The natural history of homozygous sickle-cell anaemia in Central Africa.

Authors:  H C TROWELL; A B RAPER; H F WELBOURN
Journal:  Q J Med       Date:  1957-10

6.  Present-day aspects of the sickle-cell problem.

Authors:  J VANDEPITTE
Journal:  Doc Med Geogr Trop       Date:  1955-06

7.  The distribution of the sickle-cell trait in East Africa and elsewhere, and its apparent relationship to the incidence of subtertian malaria.

Authors:  A C ALLISON
Journal:  Trans R Soc Trop Med Hyg       Date:  1954-07       Impact factor: 2.184

8.  Sickle-cell anaemia and sickle-cell trait as home- and heterozygous gene-combinations.

Authors:  H LEHMANN
Journal:  Nature       Date:  1951-06-09       Impact factor: 49.962

9.  The management of leg ulcers in sickle cell anaemia.

Authors:  M M Walshe; P F Milner
Journal:  West Indian Med J       Date:  1967-03       Impact factor: 0.171

10.  Studies on the heterogeneity of hemoglobin. IX. The use of Tris(hydroxymethyl)aminomethanehcl buffers in the anion-exchange chromatography of hemoglobins.

Authors:  T H Huisman; A M Dozy
Journal:  J Chromatogr       Date:  1965-07
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  22 in total

1.  Prevalence of sickle cell anemia: an improved outlook.

Authors:  A S Gima; J C Lee
Journal:  J Natl Med Assoc       Date:  1975-07       Impact factor: 1.798

Review 2.  Genetic modifiers of sickle cell disease.

Authors:  Martin H Steinberg; Paola Sebastiani
Journal:  Am J Hematol       Date:  2012-05-28       Impact factor: 10.047

3.  Duodenal ulcer in sickle cell disease.

Authors:  J S de Caestecker; I Bates
Journal:  Gut       Date:  1989-11       Impact factor: 23.059

4.  Prognostic significance of early vaso-occlusive complications in children with sickle cell anemia.

Authors:  Charles T Quinn; Elizabeth P Shull; Naveed Ahmad; Nancy J Lee; Zora R Rogers; George R Buchanan
Journal:  Blood       Date:  2006-08-29       Impact factor: 22.113

5.  Mild sickle-cell anaemia in Iran associated with high levels of fetal haemoglobin.

Authors:  M Haghshenass; F Ismail-Beigi; J B Clegg; D J Weatherall
Journal:  J Med Genet       Date:  1977-06       Impact factor: 6.318

6.  Endoscopic and gastric acid studies in homozygous sickle cell disease and upper abdominal pain.

Authors:  M G Lee; C H Thirumalai; S I Terry; G R Serjeant
Journal:  Gut       Date:  1989-05       Impact factor: 23.059

7.  Heights, weights, and skeletal age of Jamaican adolescents with sickle cell anaemia.

Authors:  M T Ashcroft; G R Serjeant; P Desai
Journal:  Arch Dis Child       Date:  1972-08       Impact factor: 3.791

8.  Sickle cell anemia at the Harlem Hospital Center.

Authors:  Y H Shin; L Glass; H E Evans
Journal:  J Natl Med Assoc       Date:  1974-03       Impact factor: 1.798

9.  Anti-sickling effect of dietary thiocyanate in prophylactic control of sickle cell anemia.

Authors:  O Agbai
Journal:  J Natl Med Assoc       Date:  1986-11       Impact factor: 1.798

10.  Red cell survival studies in hereditary spherocytosis.

Authors:  J S Wiley
Journal:  J Clin Invest       Date:  1970-04       Impact factor: 14.808

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