Literature DB >> 422877

Crosslink of collagen in hypertrophic scar.

T Moriguchi, D Fujimoto.   

Abstract

It is conceivable that intramolecular and intermolecular crosslinks of collagen may be involved in the formation of hypertrophic scar, but little is known about the relationship between hypertrophic scar and crosslinks of collagen. We have isolated a new crosslinking amino acid from collagen and have named it pyridinoline. In this investigation, we examined the content of pyridinoline in human normal skin, mature scar and hypertrophic scar. An appreciable amount of pyridinoline was found in collagen of hypertrophic scar, but pyridinoline is virtually absent in collagen of normal skin.

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Year:  1979        PMID： 422877     DOI： 10.1111/1523-1747.ep12530609

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN： 0022-202X            Impact factor:   8.551


  9 in total

Review 1.  Development of mast cells and importance of their tryptase and chymase serine proteases in inflammation and wound healing.

Authors:  Jeffrey Douaiher; Julien Succar; Luca Lancerotto; Michael F Gurish; Dennis P Orgill; Matthew J Hamilton; Steven A Krilis; Richard L Stevens
Journal:  Adv Immunol       Date:  2014       Impact factor: 3.543

2.  Procollagen Lysyl Hydroxylase 2 Expression Is Regulated by an Alternative Downstream Transforming Growth Factor β-1 Activation Mechanism.

Authors:  Rutger A F Gjaltema; Saskia de Rond; Marianne G Rots; Ruud A Bank
Journal:  J Biol Chem       Date:  2015-10-02       Impact factor: 5.157

3.  An enzyme-linked immunoassay for the collagen cross-link pyridinoline.

Authors:  S P Robins
Journal:  Biochem J       Date:  1982-12-01       Impact factor: 3.857

Review 4.  Feeling Things Out: Bidirectional Signaling of the Cell-ECM Interface, Implications in the Mechanobiology of Cell Spreading, Migration, Proliferation, and Differentiation.

Authors:  Andrew E Miller; Ping Hu; Thomas H Barker
Journal:  Adv Healthc Mater       Date:  2020-02-09       Impact factor: 9.933

Review 5.  NADPH oxidase enzymes in skin fibrosis: molecular targets and therapeutic agents.

Authors:  Olubukola Babalola; Andrew Mamalis; Hadar Lev-Tov; Jared Jagdeo
Journal:  Arch Dermatol Res       Date:  2013-10-24       Impact factor: 3.017

6.  Measurement of the cross linking compound, pyridinoline, in urine as an index of collagen degradation in joint disease.

Authors:  S P Robins; P Stewart; C Astbury; H A Bird
Journal:  Ann Rheum Dis       Date:  1986-12       Impact factor: 19.103

7.  Relationship between the content of lysyl oxidase-dependent cross-links in skin collagen, nonenzymatic glycosylation, and long-term complications in type I diabetes mellitus.

Authors:  B Buckingham; K M Reiser
Journal:  J Clin Invest       Date:  1990-10       Impact factor: 14.808

8.  Effect of N-(2-aminoethyl) ethanolamine on hypertrophic scarring changes in vitro: Finding novel anti-fibrotic therapies.

Authors:  Zhenping Chen; Jianhua Gu; Amina El Ayadi; Andres F Oberhauser; Jia Zhou; Linda E Sousse; Celeste C Finnerty; David N Herndon; Paul J Boor
Journal:  Toxicol Appl Pharmacol       Date:  2018-09-22       Impact factor: 4.219

9.  Increased Collagen Crosslinking in Stiff Clubfoot Tissue: Implications for the Improvement of Therapeutic Strategies.

Authors:  Jarmila Knitlova; Martina Doubkova; Adam Eckhardt; Martin Ostadal; Jana Musilkova; Lucie Bacakova; Tomas Novotny
Journal:  Int J Mol Sci       Date:  2021-11-02       Impact factor: 5.923
  9 in total

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