Literature DB >> 422856

Inhibition of murine natural killer cell-mediated cytotoxicity by pretreatment with ammonium chloride.

C A Savary, J H Phillips, E Lotzová.   

Abstract

In the present study the effect of ammonium chloride on murine natural killer (NK) cell-mediated cytotoxicity to T cell lymphoma, YAC-1 was studied. It was found that ammonium chloride treatment significantly reduced the cytotoxicity of splenic NK cells without any detectable change in cell viability. It is, therefore, suggested to avoid ammonium chloride treatment in order to obtain the realistic reflection of murine NK cell activities.

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Year:  1979        PMID： 422856     DOI： 10.1016/0022-1759(79)90055-3

Source DB:  PubMed          Journal:  J Immunol Methods        ISSN： 0022-1759            Impact factor:   2.303


  3 in total

1.  Perforin is activated by a proteolytic cleavage during biosynthesis which reveals a phospholipid-binding C2 domain.

Authors:  R Uellner; M J Zvelebil; J Hopkins; J Jones; L K MacDougall; B P Morgan; E Podack; M D Waterfield; G M Griffiths
Journal:  EMBO J       Date:  1997-12-15       Impact factor: 11.598

Review 2.  Effects of exogenous amines on mammalian cells, with particular reference to membrane flow.

Authors:  R T Dean; W Jessup; C R Roberts
Journal:  Biochem J       Date:  1984-01-01       Impact factor: 3.857

3.  Altered distribution and function of natural killer cells in murine and human Niemann-Pick disease type C1.

Authors:  Anneliese O Speak; Danielle Te Vruchte; Lianne C Davis; Anthony J Morgan; David A Smith; Nicole M Yanjanin; Louise Simmons; Ralf Hartung; Heiko Runz; Eugen Mengel; Michael Beck; Jackie Imrie; Elizabeth Jacklin; James E Wraith; Christian Hendriksz; Robin Lachmann; Celine Cognet; Rohini Sidhu; Hideji Fujiwara; Daniel S Ory; Antony Galione; Forbes D Porter; Eric Vivier; Frances M Platt
Journal:  Blood       Date:  2013-11-14       Impact factor: 22.113
  3 in total

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