Literature DB >> 422456

A system for rapid measurement of lung function in small animals.

D Holub, R Frank.   

Abstract

A semiautomated system has been developed to facilitate the rapid measurement of a variety of pulmonary functional parameters in small animals. They include lung volumes, mechanics, flow-volume curves, nitrogen washout curves, and diffusing capacity. The animals are anesthetized, intubated, and ventilated mechanically. The construction of the system is described in detail and the results obtained on rats are compared with those published by other investigators.

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Year:  1979        PMID: 422456     DOI: 10.1152/jappl.1979.46.2.394

Source DB:  PubMed          Journal:  J Appl Physiol Respir Environ Exerc Physiol        ISSN: 0161-7567


  3 in total

1.  The effect of gas exchange on multiple-breath nitrogen washout measures of ventilation inhomogeneity in the mouse.

Authors:  Mahesh Dharmakumara; G Kim Prisk; Simon G Royce; Merryn Tawhai; Bruce R Thompson
Journal:  J Appl Physiol (1985)       Date:  2014-09-11

2.  Can animal pulmonary function testing provide data for regulatory decision making?

Authors:  J J O'Neil; J A Raub
Journal:  Environ Health Perspect       Date:  1983-10       Impact factor: 9.031

Review 3.  Pulmonary function testing in small laboratory mammals.

Authors:  J J O'Neil; J A Raub
Journal:  Environ Health Perspect       Date:  1984-06       Impact factor: 9.031

  3 in total

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