Literature DB >> 4218960

Water-soluble metabolites of p-nitrophenol and 1-naphthyl N-methylcarbamate in flies and grass grubs. Formation of glucose phosphate and phosphate conjugates.

M P Heenan, J N Smith.   

Abstract

Metabolites isolated from houseflies dosed with 1-napththol or p-nitrophenol were identified as the phosphate and glucose phosphate conjugates of these phenols by titrations, hydrolysis, ionophoresis, i.r. spectra and mixed melting point. [(3)H]Carbaryl (1-naphthyl N-methylcarbamate) was metabolized by houseflies, blowflies and grass grubs to water-soluble metabolites which had chromatographic and ionophoretic behaviour similar to those of the conjugates of 1-naphthol with glucose, sulphate, phosphate and glucose 6-phosphate.

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Year:  1974        PMID: 4218960      PMCID: PMC1168497          DOI: 10.1042/bj1440303

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  13 in total

1.  Comparative detoxication. 6. The metabolism of 6-amino-4-nitro-o-cresol and 4:6-dinitro-o-cresol in locusts.

Authors:  T KIKAL; J N SMITH
Journal:  Biochem J       Date:  1959-01       Impact factor: 3.857

2.  D-Glucuronic acid in metabolism.

Authors:  H G BRAY
Journal:  Adv Carbohydr Chem       Date:  1953

3.  Detection of phosphate esters on paper chromatograms.

Authors:  H E WADE; D M MORGAN
Journal:  Nature       Date:  1953-03-21       Impact factor: 49.962

4.  Conjugation of 1-naphthol and p-nitrophenol in flies: formation of glucoside-6-phosphates.

Authors:  M P Heenan; J N Smith
Journal:  Life Sci       Date:  1967-08-15       Impact factor: 5.037

5.  Comparative detoxication. 11. Conjugations of 1-naphthol and some other phenols in houseflies and locusts.

Authors:  J N Smith; H B Turbert
Journal:  Biochem J       Date:  1964-07       Impact factor: 3.857

6.  Comparative detoxication. 13. Detoxication of aromatic acids in arachnids: arginine, glutamic acid and glutamine conjugations.

Authors:  M Hitchcock; J N Smith
Journal:  Biochem J       Date:  1964-11       Impact factor: 3.857

7.  Comparative detoxication. 9. The metabolism of some halogenated compounds by conjugation with glutathione in the locust.

Authors:  A J Cohen; J N Smith
Journal:  Biochem J       Date:  1964-03       Impact factor: 3.857

8.  Biochemical studies of toxic agents. 3. The isolation of 1- and 2-naphthylsulphuric acid and 1- and 2 naphthylglucuronide from the urine of rats dosed with 1- and 2-naphthol.

Authors:  M BERENBOM; L YOUNG
Journal:  Biochem J       Date:  1951-07       Impact factor: 3.857

9.  The conjugation of phenols with phosphate in grass grubs and flies.

Authors:  A Binning; F J Darby; M P Heenan; J N Smith
Journal:  Biochem J       Date:  1967-04       Impact factor: 3.857

10.  Comparative detoxication. The detoxication of aromatic acids by invertebrates: detection of agmatine conjugates in scorpions.

Authors:  M Hitchcock; J N Smith
Journal:  Biochem J       Date:  1966-03       Impact factor: 3.857

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