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Literature DB >> 421858

Relevance of specific activity in experimental erythrocytocide by 55Fe.

U Reincke, D Brookoff, E P Cronkite, M Hillman, D Wilcox, H Burlington.

Abstract

Iron loads between 0.20 microgram and 26 microgram, added to 5 mu Ci 59Fe, were followed for up to 150 days in mice. Relative organ uptake increased as a function of iron load in liver and kidneys while it decreased in bone marrow and blood. Several weeks after injection, all load-related differences disappeared.

Entities: Chemical Disease Species

Mesh：

Substances：
Iron Radioisotopes

Year: 1979 PMID： 421858 DOI： 10.1007/bf01920663

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

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References

11 in total

1. Selective damage to erythroblasts by 55-Fe.

Authors: U Reincke; H Burlington; E P Cronkite; M Hillman; J Laissue
Journal: Blood Date: 1975-06 Impact factor: 22.113

2. Turnover studies with 59Fe in the x-irradiated rat.

Authors: E H BELCHER; E B HARRISS; L F LAMERTON
Journal: Br J Haematol Date: 1958-10 Impact factor: 6.998

3. Role of transferrin in determining internal iron distribution.

Authors: P Pootrakul; A Christensen; B Josephson; C A Finch
Journal: Blood Date: 1977-06 Impact factor: 22.113

4. Induction of osteosarcomas and hematopoietic neoplasms by 55Fe in mice.

Authors: J A Laissue; H Burlington; E P Cronkite; U Reincke
Journal: Cancer Res Date: 1977-10 Impact factor: 12.701

Review 5. Iron metabolism and kinetics.

Authors: M Pollycove
Journal: Semin Hematol Date: 1966-10 Impact factor: 3.851

Relevance of specific activity in experimental erythrocytocide by 55Fe.

1. Selective damage to erythroblasts by 55-Fe.

2. Turnover studies with 59Fe in the x-irradiated rat.

3. Role of transferrin in determining internal iron distribution.

4. Induction of osteosarcomas and hematopoietic neoplasms by 55Fe in mice.

Review 5. Iron metabolism and kinetics.

6. Susceptibility of hematopoietic stem cells (CFU-s) to 55Fe radiation damage.

7. Active bone marrow distribution in the monkey.

8. Iron and transferrin distribution and turnover in iron-overloaded rabbits.

9. Internal iron exchange in the rat.

10. Blood volume and extracellular space (ECS) of the whole body and some organs of the rat.