Literature DB >> 421845

Effect of vitamin A deficiency on rat hepatic and colon epoxide hydrase.

A A Adekunle, T C Campbell, S C Campbell.   

Abstract

Rat liver microsomes and homogenized mucosal linings prepared from vitamin A-supplemented and deficient male rats were used in metabolic studies of 7-3H-styrene oxide. The colon tissue in deficient animals exhibits a significantly higher value of Vmax than the same tissue from vitamin-supplemented animals. The implications of this finding in addition to our earlier observation 10 is discussed in relation to colon carcinoma.

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Year:  1979        PMID： 421845     DOI： 10.1007/bf01920640

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  20 in total

1.  Computer programmes for processing enzyme kinetic data.

Authors:  W W CLELAND
Journal:  Nature       Date:  1963-05-04       Impact factor: 49.962

2.  A Note on the Kinetics of Enzyme Action.

Authors:  G E Briggs; J B Haldane
Journal:  Biochem J       Date:  1925       Impact factor: 3.857

Review 3.  Current trends in chemical carcinogenesis.

Authors:  C Heidelberger
Journal:  Fed Proc       Date:  1973-12

4.  Commentary. A perspective on the role of chemically reactive metabolites of foreign compounds in toxicity. I. Correlation of changes in covalent binding of reactivity metabolites with changes in the incidence and severity of toxicity.

Authors:  J R Gillette
Journal:  Biochem Pharmacol       Date:  1974-10-15       Impact factor: 5.858

Review 5.  Carcinogenesis by chemicals: an overview--G. H. A. Clowes memorial lecture.

Authors:  J A Miller
Journal:  Cancer Res       Date:  1970-03       Impact factor: 12.701

6.  Rat colon carcinomas associated with aflatoxin and marginal vitamin A.

Authors:  P M Newberne; A E Rogers
Journal:  J Natl Cancer Inst       Date:  1973-02       Impact factor: 13.506

7.  Chemical carcinogenesis: mechanisms and approaches to its control.

Authors:  J A Miller; E C Miller
Journal:  J Natl Cancer Inst       Date:  1971-09       Impact factor: 13.506

8.  Potential carcinogenicity of food additives and contaminants.

Authors:  P Shubik
Journal:  Cancer Res       Date:  1975-11       Impact factor: 12.701

9.  Factors modulating benzidine carcinogenicity bioassay.

Authors:  S D Vesselinovitch; K V Rao; N Mihailovich
Journal:  Cancer Res       Date:  1975-10       Impact factor: 12.701

10.  Comparative histopathological effects of aflatoxin B1 and palmotoxins B0 and G0 on some organs of different strains of the newly hatched chick (Gallus domesticus).

Authors:  J A Smith; A A Adekunle; O Bassir
Journal:  Toxicology       Date:  1975       Impact factor: 4.221
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