Literature DB >> 421843

Effects of octylguanidine on the electrical activity of Xenopus heart.

G G Re, E Meda.   

Abstract

The effects of laboratory synthesized octylguanidine are described. There is an early decease of the maximum rate of rise of the action potential with negligible reduction of the overshoot although the membrane resting potential is unchanged. Subsequently, there is a remarkable reduction of both membrane potential and overshoot, while the plateau is shortened. The former effects resemble those seen with tetrodotoxin, the latter ones, with metabolic poisons.

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Year:  1979        PMID: 421843     DOI: 10.1007/bf01920636

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  12 in total

1.  The effect of the cardiac membrane potential on the rapid availability of the sodium-carrying system.

Authors:  S WEIDMANN
Journal:  J Physiol       Date:  1955-01-28       Impact factor: 5.182

2.  The effect of alkylguanidines on mitochondrial metabolism.

Authors:  J B CHAPPELL
Journal:  J Biol Chem       Date:  1963-01       Impact factor: 5.157

3.  Studies with guanidines on the mechanism of K+ transport in yeast.

Authors:  A Peña
Journal:  FEBS Lett       Date:  1973-08-01       Impact factor: 4.124

4.  Respiratory changes induced by guanidines and cations in submitochondrial particles.

Authors:  B Lotina; M T de Gómez-Puyou; A Gómez-Puyou
Journal:  Arch Biochem Biophys       Date:  1973-11       Impact factor: 4.013

5.  On the locus of action of Na + at site I of oxidative phosphorylation.

Authors:  A Gómez-Puyou; F Sandoval; M T De Gómez-Puyou; E Chávez; E Pinto
Journal:  J Bioenerg       Date:  1972-06

6.  Membrane current and contraction in frog atrial fibres.

Authors:  H M Einwächter; H G Haas; R Kern
Journal:  J Physiol       Date:  1972-12       Impact factor: 5.182

7.  Interaction of biguanides with mitochondrial and synthetic membranes.

Authors:  G Schäfer; D Bojanowski
Journal:  Eur J Biochem       Date:  1972-05-23

8.  Existence and role of a slow inward current during the frog atrial action potential.

Authors:  O Rougier; G Vassort; D Garnier; Y M Gargouil; E Coraboeuf
Journal:  Pflugers Arch       Date:  1969       Impact factor: 3.657

9.  Effects of adrenaline on membrane inward currents during the cardiac action potential.

Authors:  G Vassort; O Rougier; D Garnier; M P Sauviat; E Coraboeuf; Y M Gargouïl
Journal:  Pflugers Arch       Date:  1969       Impact factor: 3.657

10.  Alkylguanidines as inhibitors of k transport in isolated barley roots.

Authors:  B G Lepe; E J Avila
Journal:  Plant Physiol       Date:  1975-10       Impact factor: 8.340

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