Literature DB >> 421805

Influences of temperature change on the relaxation and amplitude inhibition by noradrenaline in the rabbit jejunum.

A Hayashi, H Tanaka, T Suzuki.   

Abstract

In the rabbit jejunum, the elevation of temperature within the range of 25-37 degrees C diminished the sensitivity to noradrenaline (NA) for both the relaxation and amplitude inhibition. The relaxation by NA was mainly mediated via adrenergic beta-receptors at 25, 30 or 37 degrees C. The amplitude inhibition was mediated via alpha-receptors at 37 degrees C, and both alpha- and beta-receptors at 30 or 25 degrees C.

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Year:  1979        PMID： 421805     DOI： 10.1007/bf01917887

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  7 in total

1.  Cumulative dose-response curves. II. Technique for the making of dose-response curves in isolated organs and the evaluation of drug parameters.

Authors:  J M VAN ROSSUM
Journal:  Arch Int Pharmacodyn Ther       Date:  1963

2.  Influence of temperature on the positive inotropic effects mediated by alpha-and-beta-adrenoceptors in the isolated rabbit papillary muscle.

Authors:  M Endoh; J Wagner; H J Schümann
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1975       Impact factor: 3.000

3.  Effects of sympathetic innervation and temperature on the properties of rat heart adrenoceptors.

Authors:  G Kunos; M Nickerson
Journal:  Br J Pharmacol       Date:  1977-04       Impact factor: 8.739

4.  Effect of temperature on drug-receptor interaction in isolated canine veins.

Authors:  W J Janssens; P M Vanhoutte
Journal:  Arch Int Pharmacodyn Ther       Date:  1977-05

5.  Effect of cooling on beta-receptor mechanisms in isolated saphenous veins of the dog.

Authors:  P M Vanhoutte; J T Shepherd
Journal:  Arch Int Pharmacodyn Ther       Date:  1970-05

6.  Sensitivity changes of adrenergic -receptors of isolated ileum and trachea preparations induced by alteration of temperature.

Authors:  J Wagner; D Reinhardt; H J Schümann
Journal:  Arch Int Pharmacodyn Ther       Date:  1972-06

7.  Influence of the metabolic state on the action of phenylephrine on rabbit ileum, guinea-pig vas deferens and atrium.

Authors:  J Wagner; D Reinhardt; H J Schümann
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1973       Impact factor: 3.000
  7 in total

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