Literature DB >> 4213961

Sporicidal activity of hospital disinfectants.

J C Kelsey, I H Mackinnon, I M Maurer.   

Abstract

The sporicidal activity of hospital disinfectants was tested using two methods of test and two species of spores. Alcoholic hypochlorite and glutaraldehyde (Cidex) showed some sporicidal activity; the first was the more effective. Iodophors, formalin, and phenolics were less effective, in descending order. Chlorhexidine showed no activity.A freshly prepared solution containing 50% methanol and sufficient sodium hypochlorite to provide 2000 parts per million available chlorine in distilled water, with a contact time of 15 minutes, is suggested for the decontamination of clean, heat-sensitive instruments except those of plated metal. It must be understood that no such method can be depended upon to sterilize.The instruments should be rinsed in sterile water before use after decontamination.

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Year:  1974        PMID: 4213961      PMCID: PMC475418          DOI: 10.1136/jcp.27.8.632

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN: 0021-9746            Impact factor:   3.411


  9 in total

1.  Studies on spore germination. I. Effect of nitrogen sources on spore germination.

Authors:  Y HACHISUKA; N ASANO; N KATO; M OKAJIMA; M KITAORI; T KUNO
Journal:  J Bacteriol       Date:  1955-04       Impact factor: 3.490

2.  Defined medium for phenol coefficient tests with Salmonella typhosa and Staphylococcus aureus.

Authors:  E S WRIGHT; R A MUNDY
Journal:  J Bacteriol       Date:  1960-08       Impact factor: 3.490

3.  A comparative survey of the nutrition and physiology of mesophilic species in the genus Bacillus.

Authors:  B C J G KNIGHT; H PROOM
Journal:  J Gen Microbiol       Date:  1950-09

4.  Iodine inactivating agent in surgical scrub testing.

Authors:  A Gross; L Cofone; M B Huff
Journal:  Arch Surg       Date:  1973-02

5.  Glutaraldehyde as a bactericidal agent.

Authors:  T J Munton; A D Russell
Journal:  Br Med J       Date:  1971-08-07

6.  A bacterial spore test piece for the control of ethylene oxide sterilization.

Authors:  M M Beeby; C E Whitehouse
Journal:  J Appl Bacteriol       Date:  1965-12

7.  Symposium on bacterial spores: XII. The sporicidal properties of chemical disinfectants.

Authors:  G Sykes
Journal:  J Appl Bacteriol       Date:  1970-03

8.  Symposium on bacterial spores: VII. Recovering spores damaged by heat, ionizing radiations or ethylene oxide.

Authors:  T A Roberts
Journal:  J Appl Bacteriol       Date:  1970-03

9.  Growth inhibition of staphylococci by sodium thiosulphate.

Authors:  A Kayser; G van der Ploeg
Journal:  J Appl Bacteriol       Date:  1965-08
  9 in total
  6 in total

1.  Antimicrobial activity of UMFix tissue fixative.

Authors:  T J Cleary; A R Morales; M Nadji; M Nassiri; V Vincek
Journal:  J Clin Pathol       Date:  2005-01       Impact factor: 3.411

Review 2.  Bacterial spores and chemical sporicidal agents.

Authors:  A D Russell
Journal:  Clin Microbiol Rev       Date:  1990-04       Impact factor: 26.132

3.  Surface-decontaminating action of glutaraldehyde in the gas-aerosol phase.

Authors:  A Bovallius; P Anäs
Journal:  Appl Environ Microbiol       Date:  1977-08       Impact factor: 4.792

4.  Sporicidal activity of mixtures of alcohol and hypochlorite.

Authors:  D Coates; J E Death
Journal:  J Clin Pathol       Date:  1978-02       Impact factor: 3.411

5.  Use of buffered hypochlorite solution for disinfecting fibrescopes.

Authors:  D Coates; J E Death
Journal:  J Clin Pathol       Date:  1982-03       Impact factor: 3.411

6.  The differential susceptibility of spores from virulent and attenuated Bacillus anthracis strains to aldehyde- and hypochlorite-based disinfectants.

Authors:  Jordon K March; Marissa N Cohen; James M Lindsey; D A Millar; Chinn-Woan Lowe; Annette J Bunnell; Kim L O'Neill; G Bruce Schaalje; Richard A Robison
Journal:  Microbiologyopen       Date:  2012-10-11       Impact factor: 3.139

  6 in total

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