| Literature DB >> 4211054 |
J Kazár, R Brezina, J Urvölgyi.
Abstract
Cultivation of E strain of Rickettsia prowazeki in mouse lung resulted in a marked increase in virulence for guinea pigs following 12 passages (but not 6 passages) in both immunosuppressed and normal mice. Attempts at passaging E strain in normal guinea pigs were unsuccessful. Isolates of E strain in the chicken embryo yolk sac either from testes and peritoneal washings or from the brain of immunosuppressed guinea pigs did not show enhanced virulence for guinea pigs.Entities:
Mesh:
Year: 1973 PMID: 4211054 PMCID: PMC2481156
Source DB: PubMed Journal: Bull World Health Organ ISSN: 0042-9686 Impact factor: 9.408