Literature DB >> 4210249

Irreversible binding of ethynyl-estradiol metabolites to protein and nucleic acids as catalyzed by rat liver microsomes and mushroom tyrosinase.

H M Bolt, H Kappus.   

Abstract

Entities:  

Keywords:  Contraception; Contraceptive Agents; Contraceptive Agents, Estrogen; Contraceptive Agents, Female; Ethinyl Estradiol; Family Planning

Mesh：

Substances：

Year:  1974        PMID： 4210249     DOI： 10.1016/0022-4731(74)90126-5

Source DB:  PubMed          Journal:  J Steroid Biochem        ISSN： 0022-4731            Impact factor:   4.292


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  11 in total

1.  Decreased liver cytochrome P-450 in rats caused by norethindrone or ethynyloestradiol.

Authors:  I N White; U Muller-Eberhard
Journal:  Biochem J       Date:  1977-07-15       Impact factor: 3.857

2.  Covalent binding of drug metabolites to DNA--a tool of predictive value?

Authors:  H M Bolt; R J Laib
Journal:  Arch Toxicol       Date:  1980-11       Impact factor: 5.153

3.  Effect of rifampicin treatment on the metabolism of oestradiol and 17alpha-ethinyloestradiol by human liver microsomes.

Authors:  H M Bolt; H Kappus; M Bolt
Journal:  Eur J Clin Pharmacol       Date:  1975-06-13       Impact factor: 2.953

Review 4.  Metabolism of stilbene estrogens and steroidal estrogens in relation to carcinogenicity.

Authors:  M Metzler
Journal:  Arch Toxicol       Date:  1984-07       Impact factor: 5.153

5.  Metabolic activation of acetylenic substituents to derivatives in the rat causing the loss of hepatic cytochrome P-450 and haem.

Authors:  I N White
Journal:  Biochem J       Date:  1978-09-15       Impact factor: 3.857

6.  The significance of covalent binding of catechols to proteins in vivo.

Authors:  H Remmer; M Scheulen; H Kappus; H M Bolt
Journal:  Arch Toxicol       Date:  1977-12-30       Impact factor: 5.153

7.  Structural modifications in contraceptive steroids altering their metabolism and toxicity.

Authors:  H M Bolt
Journal:  Arch Toxicol       Date:  1977-12-30       Impact factor: 5.153

8.  The metabolism of 17 alpha-ethinyloestradiol by human liver microsomes: formation of catechol and chemically reactive metabolites.

Authors:  H S Purba; J L Maggs; M L Orme; D J Back; B K Park
Journal:  Br J Clin Pharmacol       Date:  1987-04       Impact factor: 4.335

9.  Interaction of estrone and estradiol with DNA and protein of liver and kidney in rat and hamster in vivo and in vitro.

Authors:  M Caviezel; W K Lutz; U Minini; C Schlatter
Journal:  Arch Toxicol       Date:  1984-07       Impact factor: 5.153

10.  Irreversible binding of 3-14C-antipyrine to hepatic protein in vivo and in metabolizing liver microsomes.

Authors:  S Tabarelli-Poplawski; H Uehleke
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977-03       Impact factor: 3.000
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