Literature DB >> 4201189

Effect of nalidixic acid on PBS2 bacteriophage infection of Bacillus subtilis.

A R Price, S M Fogt.   

Abstract

Infection of Bacillus subtilis by PBS2 phage, whose DNA contains uracil instead of thymine, is relatively unaffected by low concentrations of nalidixic acid which severely inhibit B. subtilis DNA synthesis. High concentrations of nalidixic acid do inhibit PBS2 DNA synthesis, but more severely reduce the burst size of PBS2 infections. Hydroxyurea blocks PBS2 DNA synthesis, preventing progeny phage production.

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Year:  1973        PMID： 4201189      PMCID： PMC356637     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  14 in total

1.  Turnover of the deoxyribonucleoside triphosphates in Escherichia coli 15 T during thymine starvation.

Authors:  J Neuhard; E Thomassen
Journal:  Eur J Biochem       Date:  1971-05-11

2.  Nalidixic acid does not inhibit bacterial transformation.

Authors:  A M Pedrini; D Geroldi; A Falaschi
Journal:  Mol Gen Genet       Date:  1972

3.  Effect of nalidixic acid on the growth of deoxyribonucleic acid bacteriophages.

Authors:  J P Baird; G J Bourguignon; R Sternglanz
Journal:  J Virol       Date:  1972-01       Impact factor: 5.103

4.  Temperature-sensitive mutants of B. subtilis defective in deoxyribonucleotide synthesis.

Authors:  G W Bazill; D Karamata
Journal:  Mol Gen Genet       Date:  1972

5.  Studies on the mode of action of nalidixic acid.

Authors:  A M Pedrini; D Geroldi; A Siccardi; A Falaschi
Journal:  Eur J Biochem       Date:  1972-02-15

6.  Effect of nalidixic acid on the growth of bacterial viruses.

Authors:  A Taketo; H Watanabe
Journal:  J Biochem       Date:  1967-04       Impact factor: 3.387

7.  Bactericidal action of nalidixic acid on Bacillus subtilis.

Authors:  T M Cook; K G Brown; J V Boyle; W A Goss
Journal:  J Bacteriol       Date:  1966-11       Impact factor: 3.490

8.  Effect of hydroxyurea on replication of bacteriophage T4 in Escherichia coli.

Authors:  H R Warner; M D Hobbs
Journal:  J Virol       Date:  1969-03       Impact factor: 5.103

9.  New deoxyribonucleic acid polymerase induced by Bacillus subtilis bacteriophage PBS2.

Authors:  A R Price; S J Cook
Journal:  J Virol       Date:  1972-04       Impact factor: 5.103

10.  Effect of nalidixic acid on deoxyribonucleic acid synthesis in bacteriophage SPO1-infected Bacillus subtilis.

Authors:  L P Gage; D J Fujita
Journal:  J Bacteriol       Date:  1969-04       Impact factor: 3.490
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  3 in total

1.  Inhibition of bacteriophage PBS2 replication in Bacillus subtilis by phleomycin.

Authors:  L Post; A R Price
Journal:  J Virol       Date:  1975-02       Impact factor: 5.103

Review 2.  Phage-Antibiotic Combination Treatments: Antagonistic Impacts of Antibiotics on the Pharmacodynamics of Phage Therapy?

Authors:  Stephen T Abedon
Journal:  Antibiotics (Basel)       Date:  2019-10-11

Review 3.  A combination therapy of Phages and Antibiotics: Two is better than one.

Authors:  Xianghui Li; Yuhua He; Zhili Wang; Jiacun Wei; Tongxin Hu; Jiangzhe Si; Guangzhao Tao; Lei Zhang; Longxiang Xie; Abualgasim Elgaili Abdalla; Guoying Wang; Yanzhang Li; Tieshan Teng
Journal:  Int J Biol Sci       Date:  2021-08-18       Impact factor: 6.580
  3 in total

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