Literature DB >> 4199412

Defective mononuclear phagocyte function in patients with myelomonocytic leukemia and in some patients with lymphoma.

M J Cline.   

Abstract

Mononuclear phagocytes from 8 of 10 patients with myelomonocytic leukemia and 2 of 9 patients with lymphoma phagocytized several species of bacteria but did not inhibit intracellular bacterial replication normally. Intracellular organisms were protected from the lethal effects of antibiotics in the medium. This defect of microbicidal function of malignant monocytes may explain in part the frequency of infection and the mechanism of antibiotic-resistant infection in some patients with malignant myeloproliferative and lymphoproliferative diseases.

Entities:  

Mesh：

Substances：

Year:  1973        PMID： 4199412      PMCID： PMC333019          DOI： 10.1172/JCI107403

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


  17 in total

1.  STUDIES ON HEAT-LABILE OPSONIN IN RABBIT SERUM.

Authors:  J G HIRSCH; B STRAUSS
Journal:  J Immunol       Date:  1964-01       Impact factor: 5.422

2.  Cellular differentiation in a murine myelomonocytic leukemia.

Authors:  M J Cline; D Metcalf
Journal:  Blood       Date:  1972-06       Impact factor: 22.113

3.  A new white cell test which measures individual phagocyte function in a mixed leukocyte population. I. A neutrophil defect in acute myelocytic leukemia.

Authors:  M J Cline
Journal:  J Lab Clin Med       Date:  1973-02

4.  Monocyte function in children with neutropenia and chronic infections.

Authors:  R L Baehner; R B Johnston
Journal:  Blood       Date:  1972-07       Impact factor: 22.113

5.  Defective bactericidal activity of monocytes in fatal granulomatous disease.

Authors:  G E Rodey; B H Park; D B Windhorst; R A Good
Journal:  Blood       Date:  1969-06       Impact factor: 22.113

6.  A defect in circulating mononuclear phagocytes in chronicgranulomatous disease of childhood.

Authors:  W C Davis; H Huber; S D Douglas; H H Fudenberg
Journal:  J Immunol       Date:  1968-11       Impact factor: 5.422

7.  Growth of human bone marrow in liquid culture.

Authors:  D W Golde; M J Cline
Journal:  Blood       Date:  1973-01       Impact factor: 22.113

8.  Leukocyte myeloperoxidase deficiency and disseminated candidiasis: the role of myeloperoxidase in resistance to Candida infection.

Authors:  R I Lehrer; M J Cline
Journal:  J Clin Invest       Date:  1969-08       Impact factor: 14.808

9.  Bactericidal Activity of Human Macrophages: Analysis of Factors Influencing the Killing of Listeria monocytogenes.

Authors:  M J Cline
Journal:  Infect Immun       Date:  1970-08       Impact factor: 3.441

10.  The kinetics of promonocytes and monocytes in the bone marrow.

Authors:  R van Furth; M M Diesselhoff-Den Dulk
Journal:  J Exp Med       Date:  1970-10-01       Impact factor: 14.307
View more
  10 in total

1.  Phagocytosis of hematopoietic cells by blast cells in blast crisis of chronic myelocytic leukemia.

Authors:  J D Shanley; M J Cline
Journal:  West J Med       Date:  1977-02

2.  Testing monocyte function.

Authors: 
Journal:  Br Med J       Date:  1978-01-21

Review 3.  Disordered function of mononuclear phagocytes in malignant disease.

Authors:  R J Sokol; G Hudson
Journal:  J Clin Pathol       Date:  1983-03       Impact factor: 3.411

Review 4.  Macrophage activation, chronic inflammation and gastrointestinal disease.

Authors:  A R Tanner; M J Arthur; R Wright
Journal:  Gut       Date:  1984-07       Impact factor: 23.059

5.  The separation, long-term cultivation, and maturation of the human monocyte.

Authors:  W D Johnson; B Mei; Z A Cohn
Journal:  J Exp Med       Date:  1977-12-01       Impact factor: 14.307

6.  Determination of the bacteriostatic capacity of neutrophils and monocytes in mixed cell populations.

Authors:  G Meuret; M Westerhausen; H Senn; S Pagon
Journal:  Blut       Date:  1977-03

7.  Phagocytosis and killing of staphylococci by human polymorphonuclear and mononuclear leucocytes.

Authors:  H A Verbrugh; R Peters; P K Peterson; J Verhoef
Journal:  J Clin Pathol       Date:  1978-06       Impact factor: 3.411

8.  Effect of autologous and homologous serum and circulating immune complexes on monocyte functions of patients with solid tumours.

Authors:  A Celada; T Aguado; P H Lambert; A Cruchaud
Journal:  Clin Exp Immunol       Date:  1980-08       Impact factor: 4.330

9.  Defective neutrophil function and microbicidal mechanisms in the myelodysplastic disorders.

Authors:  S Martin; S C Baldock; A T Ghoneim; J A Child
Journal:  J Clin Pathol       Date:  1983-10       Impact factor: 3.411

10.  Antibody-dependent haemolytic activity of human leukaemic cells.

Authors:  G Holm; M Björkholm; B Böttiger; H Mellstedt; D Pettersson; C Simonsson-Lindemalm
Journal:  Clin Exp Immunol       Date:  1980-10       Impact factor: 4.330
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.