Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Effects of local extraneural application of diphtheria toxin on the sciatic nerves of normal and protein deprived rats.

Literature DB >> 419937

Effects of local extraneural application of diphtheria toxin on the sciatic nerves of normal and protein deprived rats.

Abstract

Diphtheria toxin was locally administered around the sciatic nerves of normal and protein deprived rats aged 3, 6, 12, and 26 weeks in order to investigate the permeability of the barriers enveloping the nerves. At all ages the rats developed a reversible hind limb paralysis linked to a severe segmental demyelination, indicating passage of the toxin into the endoneurium. From 6 weeks of age the pattern of reaction differed between the protein deprived and control rats. The differences are interpreted as being partly dependent on less efficient protective barriers of the sciatic nerves of the protein deprived rats.

Entities: Disease Species

Mesh：

Substances：
Diphtheria Toxin

Year: 1979 PMID： 419937 DOI： 10.1007/bf00691892

Source DB: PubMed Journal: Acta Neuropathol ISSN： 0001-6322 Impact factor: 17.088

14 in total

1. SOME QUANTITATIVE ASPECTS OF DIPHTHERITIC NEUROPATHY.

Authors: J B CAVANAGH; J M JACOBS
Journal: Br J Exp Pathol Date: 1964-06

2. [STUDIES ON THE PERINEURIAL DIFFUSION BARRIER IN FREEZE-DRIED NERVES].

Authors: K H MARTIN
Journal: Z Zellforsch Mikrosk Anat Date: 1964-10-23

3. The effect of perinatal undernutrition on perineurial diffusion barrier to exogenous protein. An experimental study on rat sciatic nerve.

Authors: A Sima; P Sourander
Journal: Acta Neuropathol Date: 1973-05-16 Impact factor: 17.088

2. Barriers and transport properties of the perineurium. An ultrastructural study with 125I-labeled albuminin and horseradish peroxidase in normal and protein-deprived rats.

Authors: A Oldfors; B R Johansson
Journal: Acta Neuropathol Date: 1979-07-13 Impact factor: 17.088

2 in total

Effects of local extraneural application of diphtheria toxin on the sciatic nerves of normal and protein deprived rats.

1. SOME QUANTITATIVE ASPECTS OF DIPHTHERITIC NEUROPATHY.

2. [STUDIES ON THE PERINEURIAL DIFFUSION BARRIER IN FREEZE-DRIED NERVES].

3. The effect of perinatal undernutrition on perineurial diffusion barrier to exogenous protein. An experimental study on rat sciatic nerve.

4. Early changes at the node of Ranvier in segmental demyelination. Histochemical and electron microscopic observations.

5. Experimental diphtheritic neuropathy in the rat.

6. Studies on fibre size in developing sciatic nerve and spinal roots in normal, undernourished, and rehabilitated rats.

7. [The perineurium: a diffusion barrier for peroxidase in epineurial and endoneurial application].

8. Diphtheria toxin inhibits the synthesis of myelin proteolipid and basic proteins by peripheral nerve in vitro.

9. The perineurium as a diffusion barrier to protein tracers. Differences between mature and immature animals.

10. Barriers of peripheral nerve towards exogenous peroxidase in normal and protein deprived rats.

1. An outbreak of diphtheria among Swedish alcoholics.

2. Barriers and transport properties of the perineurium. An ultrastructural study with 125I-labeled albuminin and horseradish peroxidase in normal and protein-deprived rats.