Literature DB >> 4194867

Synthesis of immunoglobulin heavy and light chains by the free ribosomes of a mouse plasma cell tumor.

B Lisowska-Bernstein, M E Lamm, P Vassalli.   

Abstract

Free and membrane-bound ribosomes have been isolated from a mouse plasma cell tumor secreting immunoglobulins, and allowed to synthesize proteins under cell-free conditions. Analysis of the products of synthesis by autoradiography of immunoelectrophoresis and peptide maps indicates that both types of ribosomes synthesize heavy and light immunoglobulin chains.

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Year:  1970        PMID: 4194867      PMCID: PMC283062          DOI: 10.1073/pnas.66.2.425

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  13 in total

1.  HERITABLE VARIATION IN BENCE JONES PROTEIN STRUCTURE IN AN INBRED STRAIN OF MICE.

Authors:  M POTTER; W J DREYER; E L KUFF; K R MCINTIRE
Journal:  J Mol Biol       Date:  1964-06       Impact factor: 5.469

2.  Comparison of guinea pig gamma 1-and gamma 2-immunoglobulins by peptide mapping.

Authors:  M E Lamm; B Lisowska-Bernstein; V Nussenzweig
Journal:  Biochemistry       Date:  1967-09       Impact factor: 3.162

3.  Vectorial discharge of peptides released by puromycin from attached ribosomes.

Authors:  C M Redman; D D Sabatini
Journal:  Proc Natl Acad Sci U S A       Date:  1966-08       Impact factor: 11.205

4.  Preferential synthesis of ferritin and albumin by different populations of liver polysomes.

Authors:  S J Hicks; J W Drysdale; H N Munro
Journal:  Science       Date:  1969-05-02       Impact factor: 47.728

5.  Biosynthesis of serum proteins and ferritin by free and attached ribosomes of rat liver.

Authors:  C M Redman
Journal:  J Biol Chem       Date:  1969-08-25       Impact factor: 5.157

6.  Free and membrane-bound ribosomes in rat liver.

Authors:  J N Loeb; R Howell; G M Tomkins
Journal:  J Biol Chem       Date:  1967-05-10       Impact factor: 5.157

7.  Ribosomes in rat liver: an estimate of the percentage of free and membrane-bound ribosomes interacting with messenger RNA in vivo.

Authors:  G Blobel; V R Potter
Journal:  J Mol Biol       Date:  1967-09-28       Impact factor: 5.469

8.  Isolation and properties of polyribosomes and fragments of the endoplasmic reticulum from rat liver.

Authors:  H Bloemendal; W S Bont; M de Vries; E L Benedetti
Journal:  Biochem J       Date:  1967-04       Impact factor: 3.857

9.  Controlled proteolysis of nascent polypeptides in rat liver cell fractions. II. Location of the polypeptides in rough microsomes.

Authors:  D D Sabatini; G Blobel
Journal:  J Cell Biol       Date:  1970-04       Impact factor: 10.539

10.  A cytochemical study on the pancreas of the guinea pig. 5. In vivo incorporation of leucine-1-C14 into the chymotrypsinogen of various cell fractions.

Authors:  P SIEKEVITZ; G E PALADE
Journal:  J Biophys Biochem Cytol       Date:  1960-07
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  15 in total

1.  The selectivity and stoicheiometry of membrane binding sites for polyribosomes, ribosomes and ribosomal subunits in vitro.

Authors:  T K Shires; C M McLaughlin; H C Pitot
Journal:  Biochem J       Date:  1975-03       Impact factor: 3.857

Review 2.  Compartmentation of the rough endoplasmic reticulum.

Authors:  I F Pryme
Journal:  Mol Cell Biochem       Date:  1986-06       Impact factor: 3.396

3.  Role of membrane-bound and free polyribosomes in the synthesis of cytochrome c in rat liver.

Authors:  N F González-Cadavid; C Sáez de Córdova
Journal:  Biochem J       Date:  1974-05       Impact factor: 3.857

4.  Unreleased intracellular monoclonal macroglobulin in chronic lymphocytic leukaemia.

Authors:  D Hurez; G Flandrin; J L Preud'homme; M Seligmann
Journal:  Clin Exp Immunol       Date:  1972-02       Impact factor: 4.330

5.  Purification of 14S messenger RNA of immunoglobulin light chain that codes for a possible light-chain precursor.

Authors:  B Mach; C Faust; P Vassalli
Journal:  Proc Natl Acad Sci U S A       Date:  1973-02       Impact factor: 11.205

6.  Studies on the intracellular segregation of polyribosome-associated messenger ribonucleic acid species in the lactating guinea-pig mammary gland.

Authors:  R K Craig; A P Boulton; O S Harrison; D Parker; P N Campbell
Journal:  Biochem J       Date:  1979-09-01       Impact factor: 3.857

7.  Purification and properties of biologically active messenger RNA for a myeloma light chain.

Authors:  D Swan; H Aviv; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1972-07       Impact factor: 11.205

8.  Insulin biosynthesis: studies of Islet polyribosomes (nascent peptides-sucrose gradient analysis-gel filtration).

Authors:  M A Permutt; D M Kipnis
Journal:  Proc Natl Acad Sci U S A       Date:  1972-02       Impact factor: 11.205

9.  Biologically and chemically pure mRNA coding for a mouse immunoglobulin L-chain prepared with the aid of antibodies and immobilized oligothymidine.

Authors:  I Schechter
Journal:  Proc Natl Acad Sci U S A       Date:  1973-08       Impact factor: 11.205

10.  Virus-specific messenger RNA and nascent polypeptides in polyribosomes of cells replicating murine sarcoma-leukemia viruses.

Authors:  G Vecchio; N Tsuchida; G Shanmugam; M Green
Journal:  Proc Natl Acad Sci U S A       Date:  1973-07       Impact factor: 11.205

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