Literature DB >> 4192271

Cellular sites of immunologic unresponsiveness.

J M Chiller, G S Habicht, W O Weigle.   

Abstract

The reconstitution of the immune response of lethally irradiated mice to human gamma-globulin is dependent on the synergistic action of bone marrow with thymus cells. Immunologic unresponsiveness appears to involve a functional defect at each of these cellular levels, inasmuch as neither bone marrow nor thymus cells from unresponsive donors are capable of demonstrating synergism in combination with their normal counterpart.

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Year:  1970        PMID： 4192271      PMCID： PMC282942          DOI： 10.1073/pnas.65.3.551

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  16 in total

1.  Studies on the induction of immunologic unresponsiveness. II. Kinetics.

Authors:  E S Golub; W O Weigle
Journal:  J Immunol       Date:  1967-09       Impact factor: 5.422

2.  Immune paralysis of thymus cells by bovine serum albumin.

Authors:  R B Taylor
Journal:  Nature       Date:  1968-11-09       Impact factor: 49.962

3.  A modification of the hemolytic plaque assay for use with protein antigens.

Authors:  E S Golub; R I Mishell; W O Weigle; R W Dutton
Journal:  J Immunol       Date:  1968-01       Impact factor: 5.422

Review 4.  Cell interaction in antibody synthesis.

Authors:  D W Talmage; H Hemmingsen
Journal:  J Allergy       Date:  1969-06

5.  Application of a sensitive radial immunodiffusion method for the detection of thyroglobulin autoprecipitins.

Authors:  J G Feinberg; C W Hill; D Doniach; I M Roitt
Journal:  Int Arch Allergy Appl Immunol       Date:  1969

6.  The thymus and the precursors of antigen reactive cells.

Authors:  J F Miller; G F Mitchell
Journal:  Nature       Date:  1967-11-18       Impact factor: 49.962

7.  Role of the thymus in tolerance. I. Tolerance to bovine gamma globulin in thymectomized, irradiated rats grafted with thymus from tolerant donors.

Authors:  K Isaković; S B Smith; B H Waksman
Journal:  J Exp Med       Date:  1965-12-01       Impact factor: 14.307

8.  Cell to cell interaction in the immune response. II. The source of hemolysin-forming cells in irradiated mice given bone marrow and thymus or thoracic duct lymphocytes.

Authors:  G F Mitchell; J F Miller
Journal:  J Exp Med       Date:  1968-10-01       Impact factor: 14.307

9.  Antibody formation in vitro.

Authors:  M FISHMAN
Journal:  J Exp Med       Date:  1961-12-01       Impact factor: 14.307

10.  Persistence of immunogenicity of antigen after uptake by macrophages.

Authors:  E R Unanue; B A Askonas
Journal:  J Exp Med       Date:  1968-05-01       Impact factor: 14.307
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  52 in total

1.  Tolerance induction and maintenance in primed lymphocytes.

Authors:  J D Levich; W O Weigle
Journal:  Surv Immunol Res       Date:  1985

2.  Biological insights from clinical trials with anti-TNF therapy.

Authors:  M Feldmann; P Charles; P Taylor; R N Maini
Journal:  Springer Semin Immunopathol       Date:  1998

3.  Genetically transferred central and peripheral immune tolerance via retroviral-mediated expression of immunogenic epitopes in hematopoietic progenitors or peripheral B lymphocytes.

Authors:  E T Zambidis; A Kurup; D W Scott
Journal:  Mol Med       Date:  1997-03       Impact factor: 6.354

4.  Studies on immunological paralysis. X. Cellular characteristics of the induction and loss of tolerance to levan (Polyfructose).

Authors:  J J Miranda; H Zola; J G Howard
Journal:  Immunology       Date:  1972-12       Impact factor: 7.397

5.  Difference in the target cells for tolerance induction in relation to the dose of tolerogen.

Authors:  Y Katsura; S Kawaguchi; S Muramatsu
Journal:  Immunology       Date:  1972-10       Impact factor: 7.397

6.  Effect of allogeneic cell interaction on the primary immune response in vitro. Cell types involved in suppression and stimulation of antibody synthesis.

Authors:  O Sjöberg
Journal:  Clin Exp Immunol       Date:  1972-11       Impact factor: 4.330

7.  Control of autoantibody affinity by selection against amino acid replacements in the complementarity-determining regions.

Authors:  M Børretzen; I Randen; E Zdárský; O Førre; J B Natvig; K M Thompson
Journal:  Proc Natl Acad Sci U S A       Date:  1994-12-20       Impact factor: 11.205

8.  Epitope-specific tolerance induction with an engineered immunoglobulin.

Authors:  E T Zambidis; D W Scott
Journal:  Proc Natl Acad Sci U S A       Date:  1996-05-14       Impact factor: 11.205

9.  Rapid breaking of tolerance against Escherichia coli lipopolysaccharide in vivo and in vitro.

Authors:  O Sjöberg
Journal:  J Exp Med       Date:  1972-04-01       Impact factor: 14.307

10.  Studies on immunological paralysis. IX. The immunogenicity and tolerogenicity of levan (polyfructose) in mice.

Authors:  J J Miranda
Journal:  Immunology       Date:  1972-12       Impact factor: 7.397
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