Literature DB >> 418900

[Effect of methotrexate on glycolysis of leukemia L 1210 cells cultivated in vitro].

Y Carpentier, B Desoize, C Rollet, J C Jardillier.   

Abstract

Methotrexate, at non lethal doses, alters the glycolysis of leukaemic L 1210 cells. Glucose uptake and lactate excretion are increased but lactate/glucose ratio remains constant. The activity of glycolytic enzymes in the cytoplasm is increased and the level of intracellular ATP is greatly enhanced.

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Year:  1978        PMID: 418900

Source DB:  PubMed          Journal:  C R Acad Hebd Seances Acad Sci D


  1 in total

1.  The use of 1H spin echo NMR and HPLC to confirm doxorubicin induced depletion of glutathione in the intact HeLa cell.

Authors:  M al-Kabban; I D Watson; M J Stewart; J Reglinski; W E Smith; C J Suckling
Journal:  Br J Cancer       Date:  1988-06       Impact factor: 7.640

  1 in total

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