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Literature DB >> 4181977

Prevention of Rh hemolytic disease of the newborn.

E R Jennings, H H Dibbern, F H Hodell, C H Monroe, N H Peckham, J F Sullivan, W Pollack.

Abstract

Rh(o)(D)-Immune Globulin was given to 322 Rh-negative women delivered of ABO-compatible, Rh-positive infants with no apparent failures to suppress Rh sensitization. In contrast, 32 of 305 mothers of a control group made Rh antibody during the six months following delivery. In subsequent pregnancies, 69 women administered RhoGAM had no evidence of isoimmunization after delivery while six of forty mothers of the control study produced anti-Rh. RhoGAM, given within 72 hours of delivery in the amounts employed, was effective for suppression of Rh immunization.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 1969 PMID： 4181977 PMCID： PMC1503290

Source DB: PubMed Journal: Calif Med ISSN： 0008-1264

9 in total

4 in total

Prevention of Rh hemolytic disease of the newborn.

1. DEMONSTRATION OF FETAL ERYTHROCYTES IN MATERNAL CIRCULATION.

2. MECHANISMS OF ISOIMMUNIZATION. I. THE TRANSPLACENTAL PASSAGE OF FETAL ERYTHROCYTES IN HOMOSPECIFIC PREGNANCIES.

3. TRANSPLACENTAL TRANSMISSION OF FETAL ERYTHROCYTES.

4. Prevention of Rh isoimmunization. Progress report of the clinical trial in mothers.

5. Prevention of Rh-haemolytic disease.

6. Antibodies of Rh isoimmunization.

7. Long Beach (California) experience with Rh immunoglobulin.

8. Rh isoimmunization: its incidence, timing, and relationship to fetal-maternal hemorrhage.

9. Prevention of Rh sensitization from fetomaternal microtransfusions.

1. Suppression of rh sensitization.

2. Proven and possible future uses of anti-rh gamma globulin.

3. Prevention of erythroblastosis with anti-rh gamma globulin.

4. Amniocentesis.