Literature DB >> 418125

Comparative toxicity of netilmicin and gentamicin in squirrel monkeys (Saimiri sciureus).

M Igarashi, J K Levy, J Jerger.   

Abstract

Netilmicin was found to be less toxic than gentamicin when administered at comparable dosage levels to squirrel monkeys (Saimiri sciureus). This finding is based upon data obtained from the following determinations: length of survival period; change in body weight; observation of general change in behavior after daily injection; ataxia, as measured by the squirrel monkey platform-runway test; acoustic reflex threshold; levels of blood urea nitrogen and serum creatinine (and pathology of the kidney); and microbiological antibiotic assay.

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Year:  1978        PMID： 418125     DOI： 10.1093/infdis/137.4.476

Source DB:  PubMed          Journal:  J Infect Dis        ISSN： 0022-1899            Impact factor:   5.226


  10 in total

1.  Effects of noise overexposure on tone detection in noise in nonhuman primates.

Authors:  Samantha N Hauser; Jane A Burton; Evan T Mercer; Ramnarayan Ramachandran
Journal:  Hear Res       Date:  2017-11-09       Impact factor: 3.208

2.  Apoptosis in renal proximal tubules of rats treated with low doses of aminoglycosides.

Authors:  M El Mouedden; G Laurent; M P Mingeot-Leclercq; H S Taper; J Cumps; P M Tulkens
Journal:  Antimicrob Agents Chemother       Date:  2000-03       Impact factor: 5.191

3.  Prospective comparative study of efficacy and toxicity of netilmicin and amikacin.

Authors:  B V Bock; P H Edelstein; R D Meyer
Journal:  Antimicrob Agents Chemother       Date:  1980-02       Impact factor: 5.191

4.  Treatment of LD100 Escherichia coli septic shock with netilmicin and methylprednisolone in baboons.

Authors:  D J Flournoy; L T Archer; B K Beller; R Passey; L B Hinshaw
Journal:  Med Microbiol Immunol       Date:  1986       Impact factor: 3.402

5.  Univariate and multivariate analyses of risk factors predisposing to auditory toxicity in patients receiving aminoglycosides.

Authors:  J M Gatell; F Ferran; V Araujo; M Bonet; E Soriano; J Traserra; J G SanMiguel
Journal:  Antimicrob Agents Chemother       Date:  1987-09       Impact factor: 5.191

6.  Pharmacokinetic properties of netilmicin in newborn infants.

Authors:  J D Siegel; G H McCracken; M L Thomas; N Threlkeld
Journal:  Antimicrob Agents Chemother       Date:  1979-02       Impact factor: 5.191

7.  Histological evaluation of ototoxic reaction due to some aminoglycoside antibiotics.

Authors:  F Bamonte; L Parravicini; A Arpini
Journal:  Arch Otorhinolaryngol       Date:  1980

Review 8.  [Tobramycin concentrations in human renal tissue (author's transl)].

Authors:  O Brückner; U Kroening; R Nagel
Journal:  Infection       Date:  1979       Impact factor: 3.553

9.  Comparative synergistic activity of netilmicin-piperacillin versus gentamicin-piperacillin.

Authors:  K Machka; W Baierl; I Braveny
Journal:  Eur J Clin Microbiol       Date:  1982-08       Impact factor: 3.267

10.  Prospective randomized double-blind comparison of nephrotoxicity and auditory toxicity of tobramycin and netilmicin.

Authors:  J M Gatell; J G SanMiguel; V Araujo; L Zamora; J Maña; M Ferrer; M Bonet; M Bohe; M T Jimenez de Anta
Journal:  Antimicrob Agents Chemother       Date:  1984-11       Impact factor: 5.191
  10 in total

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