Induction of intrauterine adhesions in experimental animals and in women.

Intrauterine adhesions were induced in rats, rabbits and monkeys with fibroblast carrying polyvinyl sponges. Fertility studies have shown that these adhesions may serve as a method of contraception. Following successful studies in the animals, induction of intrauterine adhesions by the same technique was clinically applied in four women in order to reduce excessive uterine bleeding in benign uterine lesions.