Literature DB >> 41717

Metabolic acidosis in patients receiving anticonvulsants.

B Nagai, I Matsuda, T Kondo, N Taniguchi, S Arashima, T Mitsuyama, Y Oka, M Honma.   

Abstract

Blood pH, bicarbonate, PCO2, serum calcium, alkaline phosphatase and red cell carbonic anhydrase were measured in 37 selected patients receiving anticonvulsants. Patients with metabolic acidosis showed a high incidence of hypocalcemia with increased alkaline phosphatase and a significant reduction of carbonic anhydrase-B activity. High iPTH levels were found in 13 patients, but this was not correlated with acid-base balance status. Anticonvulsant drugs seemed to inactive carbonic anhydrase-B activity. Metabolic acidosis might be one of the factors causing a disturbance of calcium metabolism in these patients.

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 41717     DOI： 10.1007/bf00442432

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN： 0340-6199            Impact factor:   3.183


  13 in total

1.  Letter: Anticonvulsants, acetazolamide and osteomalacia.

Authors:  L E Mallette
Journal:  N Engl J Med       Date:  1975-09-25       Impact factor: 91.245

2.  Osteomalacia associated with anticonvulsant drug therapy in mentally retarded children.

Authors:  K G Tolman; W Jubiz; J J Sannella; J A Madsen; R E Belsey; R S Goldsmith; J W Freston
Journal:  Pediatrics       Date:  1975-07       Impact factor: 7.124

3.  Inhibition of carbonic anhydrase by parathyroid hormone and cyclic AMP in rat renal cortex in vitro.

Authors:  N Beck; K S Kim; M Wolak; B B Davis
Journal:  J Clin Invest       Date:  1975-01       Impact factor: 14.808

4.  Vitamin D-dependency rickets in institutionalized, mentally retarded children on long term anticonvulsant therapy. II. The response to 25-hydroxycholecalciferol and to vitamin D2.

Authors:  N Maclaren; F Lifshitz
Journal:  Pediatr Res       Date:  1973-11       Impact factor: 3.756

5.  Purification and properties of human erythrocyte carbonic anhydrases.

Authors:  J M Armstrong; D V Myers; J A Verpoorte; J T Edsall
Journal:  J Biol Chem       Date:  1966-11-10       Impact factor: 5.157

6.  Renal tubular acidosis and skeletal demineralization in patients on long-term anticonvulsant therapy.

Authors:  I Matsuda; Y Takekoshi; N Shida; K Fujieda; B Nagai
Journal:  J Pediatr       Date:  1975-08       Impact factor: 4.406

7.  Inactive form of erythrocyte carbonic anhydrase B in patients with primary renal tubular acidosis.

Authors:  T Kondo; N Taniguchi; K Taniguchi; I Matsuda; M Murao
Journal:  J Clin Invest       Date:  1978-09       Impact factor: 14.808

8.  Estimations of active and inactive carbonic anhydrase isozyme B in human red cells.

Authors:  T Kondo; N Taniguchi; M Murao; E Takakuwa
Journal:  Clin Chim Acta       Date:  1975-05-01       Impact factor: 3.786

9.  Enzymatically inactive red cell carbonic anhydrase B in a family with renal tubular acidosis.

Authors:  E Shapira; Y Ben-Yoseph; F G Eyal; A Russell
Journal:  J Clin Invest       Date:  1974-01       Impact factor: 14.808

10.  Plasma 1,25-dihydroxyvitamin D levels in patients receiving anticonvulsant drugs.

Authors:  W Jubiz; M R Haussler; T A McCain; K G Tolman
Journal:  J Clin Endocrinol Metab       Date:  1977-04       Impact factor: 5.958
View more
  1 in total

1.  Pseudohypoparathyroidism type II and anticonvulsant rickets.

Authors:  I Matsuda; Y Takekoshi; M Tanaka; N Matsuura; B Nagai; Y Seino
Journal:  Eur J Pediatr       Date:  1979       Impact factor: 3.183
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.