Literature DB >> 4169222

Complement and lysozyme requirements for spirochetolysis in guinea pig serum.

T A Nevin, W J Guest.   

Abstract

During experiments on the immunological immobilization of treponemes, several cultured strains were lysed in the guinea pig serum used as a source of complement. In further studies employing Borrelia vincentii, lysis, observed by darkfield, appeared as swelling and some beading of the cells. Complete disruption eventuated. Untreated guinea pig serum was strongly lytic, whereas little or no lysis occurred in bentonite-adsorbed samples. Activity was restored to these samples by adding commercially obtained crystalline egg-white lysozyme. Serum samples which had been heated, absorbed with aggregates of human gamma-globulin, or treated with ethylenediaminetetraacetate to remove, or inactivate, complement also lost spirochetolytic activity.

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Year:  1967        PMID： 4169222      PMCID： PMC276836          DOI： 10.1128/jb.94.5.1388-1393.1967

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  10 in total

1.  EFFECT OF NUTRITIONAL AND PHYSIOLOGICAL FACTORS ON THE REACTION BETWEEN LACTOBACILLUS PLANTARUM AND MURAMIDASE.

Authors:  J T HOLDEN; J N VANBALGOOY
Journal:  Biochem Biophys Res Commun       Date:  1965-05-03       Impact factor: 3.575

2.  Enhancement by lysozyme of the sensitivity of Treponema pallidum immobilization tests.

Authors:  J F KENT; J B DE WEERDT
Journal:  Br J Vener Dis       Date:  1963-03

3.  Influence of lysozyme upon the treponeme immobilization reaction.

Authors:  M METZGER; P H HARDY; E E NELL
Journal:  Am J Hyg       Date:  1961-03

4.  Partially defined medium for the cultivation of Borrelia vincentil.

Authors:  T A NEVIN; E G HAMPP
Journal:  J Bacteriol       Date:  1959-08       Impact factor: 3.490

5.  Studies on the role of Ca++ and Mg++ in complement fixation and immune hemolysis. II. The essential role of calcium in complement fixation.

Authors:  L LEVINE; K M COWAN; A G OSLER; M M MAYER
Journal:  J Immunol       Date:  1953-11       Impact factor: 5.422

6.  The determination of lysozyme.

Authors:  A N SMOLELIS; S E HARTSELL
Journal:  J Bacteriol       Date:  1949-12       Impact factor: 3.490

7.  Lysozyme and immune bacteriolysis.

Authors:  A A Glynn; C M Milne
Journal:  Nature       Date:  1965-09-18       Impact factor: 49.962

8.  Immobilization of certain cultured treponemes in sera from syphilitic humans.

Authors:  W J Guest; T A Nevin; M L Thomas; J A Adams
Journal:  J Bacteriol       Date:  1967-03       Impact factor: 3.490

9.  Interaction of the rheumatoid factor with antigen-antibody complexes and aggregated gamma globulin.

Authors:  G M EDELMAN; H G KUNKEL; E C FRANKLIN
Journal:  J Exp Med       Date:  1958-07-01       Impact factor: 14.307

10.  The complement-dependent bacteriolytic activity of normal human serum. I. The effect of pH and ionic strength and the role of lysozyme.

Authors:  A C WARDLAW
Journal:  J Exp Med       Date:  1962-06-01       Impact factor: 14.307
  10 in total
  3 in total

1.  Lytic effect of trypsin, lysozyme, and complement on Treponema pallidum.

Authors:  R H Jones; T A Nevin; W J Guest; L C Logan
Journal:  Br J Vener Dis       Date:  1968-09

2.  Identification of the primary mechanism of complement evasion by the periodontal pathogen, Treponema denticola.

Authors:  J V McDowell; J Frederick; D P Miller; M P Goetting-Minesky; H Goodman; J C Fenno; R T Marconi
Journal:  Mol Oral Microbiol       Date:  2010-12-03       Impact factor: 3.563

3.  Characterization of the cytoplasmic fibrils of Treponema refringens (Nichols).

Authors:  S R Eipert; S H Black
Journal:  Arch Microbiol       Date:  1979-03-12       Impact factor: 2.552
  3 in total

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