| Literature DB >> 416303 |
W F Bremner, K M Taylor, S Baird, J E Thomson, J A Thomson, J G Ratcliffe, T D Lawrie, W H Bain.
Abstract
Marked alterations in levels of circulating thyroid hormone were found in patients undergoing cardiopulmonary bypass with a rise in the free thyroxine and a fall in the free triiodothyronine levels. Studies using thyrotropin-releasing hormone during bypass demonstrated a blunted response to this stimulus. This reduced response is related to changes in thyroid hormone levels and it is suggested that bypass surgery may have a direct inhibitory action on thyroid-stimulating hormone release at the hypothalamo-pituitary level. The potential significance of these hormonal changes is discussed.Entities:
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Year: 1978 PMID: 416303
Source DB: PubMed Journal: J Thorac Cardiovasc Surg ISSN: 0022-5223 Impact factor: 5.209