Literature DB >> 416170

Studies on the chemical composition of lipopolysaccharide from Neisseria meningitidis group B.

G A Limjuco, Y D Karkhanis, J Y Zeltner, R Z Maigetter, J J King, D J Carlo.   

Abstract

A lipopolysaccharide was isolated from Neisseria meningitidis group B by phenol/water extraction and purified by differential ultracentrifugation. This preparation exhibited endotoxic properties as shown by the limulus-lysate assay. Mild acid hydrolysis of the lipopolysaccharides yielded a lipid A fraction and a polysaccharide fraction. The lipid A fraction contained fatty acids, phosphorus and glucosamine. Analysis of the polysaccharide fraction revealed the presence of glucose, galactose, glucosamine, 2-keto-3-deoxyoctonic acid and phosphorus. There was no heptose.

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Year:  1978        PMID: 416170     DOI: 10.1099/00221287-104-2-187

Source DB:  PubMed          Journal:  J Gen Microbiol        ISSN: 0022-1287


  5 in total

Review 1.  The meningococcus and mechanisms of pathogenicity.

Authors:  I W DeVoe
Journal:  Microbiol Rev       Date:  1982-06

2.  Purification and characterization of smooth and rough lipopolysaccharides from Brucella abortus.

Authors:  E Moreno; M W Pitt; L M Jones; G G Schurig; D T Berman
Journal:  J Bacteriol       Date:  1979-05       Impact factor: 3.490

3.  Immunological cross-reaction between a naturally occurring galactan, agarose, and an LPS locus for immune lysis of Neisseria meningitidis by human sera.

Authors:  J M Griffiss; D K Goroff
Journal:  Clin Exp Immunol       Date:  1981-01       Impact factor: 4.330

4.  Isolation and characterization of the outer membrane and lipopolysaccharide from Eikenella corrodens.

Authors:  A Progulske; S C Holt
Journal:  Infect Immun       Date:  1984-01       Impact factor: 3.441

5.  Heterogeneity and variation among Neisseria meningitidis lipopolysaccharides.

Authors:  C M Tsai; R Boykins; C E Frasch
Journal:  J Bacteriol       Date:  1983-08       Impact factor: 3.490

  5 in total

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