Literature DB >> 4160943

Antiserum to immunoglobulin A: Inhibition of cell-mediated demyelination in tissue culture.

G F Winkler, B G Arnason.   

Abstract

Lymph node cells from rats immunized with sciatic nerve in Freund's adjuvant demyelinate trigeminal ganglion cultures. Rabbit antiserum to rat immunoglobulin A blocks this cytodestructive event. The antiserum may act by combining with IgA on the lymphoid cell surface, preventing the interaction of cell-bound antibody and tissue anitigen.

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Year:  1966        PMID: 4160943     DOI: 10.1126/science.153.3731.75

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  2 in total

1.  The effect of antisera against rat immunoglobulins on cellular transfer of experimental allergic encephalomyelitiin Lewis rats.

Authors:  W P Richardson; P Y Paterson
Journal:  Clin Exp Immunol       Date:  1970-03       Impact factor: 4.330

2.  Herpes simplex virus-host cell relationships in organized cultures of mammalian nerve tissues.

Authors:  L A Feldman; R D Sheppard; M B Bornstein
Journal:  J Virol       Date:  1968-06       Impact factor: 5.103

  2 in total

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