Literature DB >> 4155979

Antagonism of inhibitory amino acid action by tubocurarine.

D R Curtis, C J Game, R M McCulloch.   

Abstract

A comparison has been made of the antagonism by microelectrophoretically administered (+)-tubocurarine, bicuculline methochloride and strychnine of the inhibition of spinal interneurones and Renshaw cells in the cat by glycine and gamma-aminobutyric acid. The results indicate that (+)-tubocurarine would be of little use in assessing which of these amino acids was the transmitter at central inhibitory synapses.

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Year:  1974        PMID: 4155979      PMCID: PMC1776924          DOI: 10.1111/j.1476-5381.1974.tb09693.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


  8 in total

1.  Convulsive properties of d-tubocurarine and cortical inhibition.

Authors:  R G Hill; M A Simmonds; D W Straughan
Journal:  Nature       Date:  1972-11-03       Impact factor: 49.962

2.  Antagonism between bicuculline and GABA in the cat brain.

Authors:  D R Curtis; A W Duggan; D Felix; G A Johnston; H McLennan
Journal:  Brain Res       Date:  1971-10-08       Impact factor: 3.252

3.  Bicuculline, an antagonist of GABA and synaptic inhibition in the spinal cord of the cat.

Authors:  D R Curtis; A W Duggan; D Felix; G A Johnston
Journal:  Brain Res       Date:  1971-09-10       Impact factor: 3.252

4.  Bicuculline methochloride as a GABA antagonist.

Authors:  G A Johnston; P M Beart; D R Curtis; C J Game; R M McCulloch; R M Maclachlan
Journal:  Nat New Biol       Date:  1972-12-13

5.  Amino acid antagonists and the depression of cuneate neurones by -aminobutyric acid (GABA) and glycine.

Authors:  R G Hill; M A Simmonds; D W Straughan
Journal:  Br J Pharmacol       Date:  1973-03       Impact factor: 8.739

Review 6.  Amino acid transmitters in the mammalian central nervous system.

Authors:  D R Curtis; G A Johnston
Journal:  Ergeb Physiol       Date:  1974

7.  A method for comparing the potencies of -aminobutyric acid antagonists on single cortical neurones using micro-iontophoretic techniques.

Authors:  R G Hill; M A Simmonds
Journal:  Br J Pharmacol       Date:  1973-05       Impact factor: 8.739

8.  A comparative study of some convulsant substances as gamma-aminobutyric acid antagonists in the feline cerebral cortex.

Authors:  R G Hill; M A Simmonds; D W Straughan
Journal:  Br J Pharmacol       Date:  1973-09       Impact factor: 8.739

  8 in total
  2 in total

1.  Vasopressin release produced in anaesthetized cats by antagonists of gamma-aminobutyric acid and glycine.

Authors:  W Feldberg; M Rocha e Silva
Journal:  Br J Pharmacol       Date:  1978-01       Impact factor: 8.739

2.  Antagonism of gamma-aminobutyric acid and glycine by convulsants in the cuneate nucleus of cat.

Authors:  R G Hill; M A Simmonds; D W Straughan
Journal:  Br J Pharmacol       Date:  1976-01       Impact factor: 8.739

  2 in total

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