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Literature DB >> 4154117

Prostaglandins, kinin and inflammation in the rat.

Abstract

1 Prostaglandin E(1) and bradykinin exert synergistic effects on vascular permeability in rat skin and in rat paws. Prostaglandin E(2) is inactive in this respect.2 Prostaglandin F(2alpha) reduces the bradykinin response in rat skin but not in rat paws. It also markedly reduces the response of the skin to dextran, 5-hydroxytryptamine and histamine.3 Prostaglandin E(1) and dextran exert synergistic effects in rat skin when threshold doses of each agent are used.4 Rats genetically resistant to dextran fail to respond to intradermal dextran in the presence of prostaglandin E(1).

Entities: Chemical Disease Species

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Year: 1974 PMID： 4154117 PMCID： PMC1776644 DOI： 10.1111/j.1476-5381.1974.tb08566.x

Source DB: PubMed Journal: Br J Pharmacol ISSN： 0007-1188 Impact factor: 8.739

8 in total

1. A simple method for the quantitative extraction of dye extravasated into the skin.

Authors: M Harada; M Takeuchi; T Fukao; K Katagiri
Journal: J Pharm Pharmacol Date: 1971-03 Impact factor: 3.765

2. Skin reactions to prostaglandins.

Authors: P C Freeman; G B West
Journal: J Pharm Pharmacol Date: 1972-05 Impact factor: 3.765

3. Parallel assay of prostaglandin-like activity in rat inflammatory exudate by means of cascade superfusion.

Authors: A L Willis
Journal: J Pharm Pharmacol Date: 1969-02 Impact factor: 3.765

4. Further experiments to establish that the analgesic action of aspirin-like drugs depends on the inhibition of prostaglandin biosynthesis.

Authors: S H Ferreira; S Moncada; J R Vane
Journal: Br J Pharmacol Date: 1973-03 Impact factor: 8.739

5. Letter: Prostaglandins as regulators of bradykinin responses.

Authors: G Thomas; G B West
Journal: J Pharm Pharmacol Date: 1973-09 Impact factor: 3.765

6. Bradykinin and oedema formation in heated paws of rats.

Authors: M S Starr; G B West
Journal: Br J Pharmacol Chemother Date: 1967-09

7. Cutaneous reactions to intradermal prostaglandins.

Authors: P Crunkhorn; A L Willis
Journal: Br J Pharmacol Date: 1971-01 Impact factor: 8.739

8. Rats resistant to the dextran anaphylactoid reaction.

Authors: J M HARRIS; G B WEST
Journal: Br J Pharmacol Chemother Date: 1963-06

8 in total

11 in total

1. Proceedings: Prostaglandin D1 inhibits the increase in vascular permeability in rat skin produced by prostaglandin E1, E2 and D2.

Authors: R J Flower; W P Kingston
Journal: Br J Pharmacol Date: 1975-10 Impact factor: 8.739

10. Decreases in histamine forming enzyme activity of non-metastasizing fibrosarcomas in hamsters with progressive tumor growth.

Authors: T C Moore; L E Koppelman; C A Lemmi
Journal: Ann Surg Date: 1978-08 Impact factor: 12.969

Prostaglandins, kinin and inflammation in the rat.

1. A simple method for the quantitative extraction of dye extravasated into the skin.

2. Skin reactions to prostaglandins.

3. Parallel assay of prostaglandin-like activity in rat inflammatory exudate by means of cascade superfusion.

4. Further experiments to establish that the analgesic action of aspirin-like drugs depends on the inhibition of prostaglandin biosynthesis.

5. Letter: Prostaglandins as regulators of bradykinin responses.

6. Bradykinin and oedema formation in heated paws of rats.

7. Cutaneous reactions to intradermal prostaglandins.

8. Rats resistant to the dextran anaphylactoid reaction.

1. Proceedings: Prostaglandin D1 inhibits the increase in vascular permeability in rat skin produced by prostaglandin E1, E2 and D2.

Review 2. Kallikreins and kinins: mediators in inflammatory joint disease?

3. A possible role of prostaglandins and bradykinin as a trigger of exudation in carrageenin-induced rat pleurisy.

4. Stimulation of gastric secretion by prostaglandin F2 alpha in rats.

5. Inflammatory effects of prostaglandin D2 in rat and human skin.

6. The modulation of enhanced vascular permeability by prostaglandins through alterations in blood flow (hyperemia).

7. Mechanism of noradrenaline potentiation by prostaglandin E2 in rat mesenteric artery.

8. Human synovial fibroblasts: the relationships between cyclic AMP, bradykinin, and prostaglandins.

9. On the ability of prostaglandin E1, and arachidonic acid to modulate experimentally induced oedema in the rat paw.

10. Decreases in histamine forming enzyme activity of non-metastasizing fibrosarcomas in hamsters with progressive tumor growth.