Literature DB >> 4151402

Hydroxylation of the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) by rat liver microsomes.

H E May, R Boose, D J Reed.   

Abstract

Entities:  

Mesh：

Substances：

Year:  1974        PMID： 4151402     DOI： 10.1016/0006-291x(74)90948-6

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


× No keyword cloud information.
  11 in total

1.  Intracarotid infusion of ACNU and BCNU as adjuvant therapy of malignant gliomas. Clinical aspects and critical considerations.

Authors:  L Papavero; F Loew; H Jaksche
Journal:  Acta Neurochir (Wien)       Date:  1987       Impact factor: 2.216

2.  Effects of elevated temperature on misonidazole O-demethylation by mouse liver microsomes: kinetic and stability studies of a model mixed-function oxidase reaction.

Authors:  M I Walton; N M Bleehen; P Workman
Journal:  Cancer Chemother Pharmacol       Date:  1989       Impact factor: 3.333

Review 3.  Intestinal and liver toxicity of antineoplastic drugs.

Authors:  G B McDonald; N Tirumali
Journal:  West J Med       Date:  1984-02

4.  Distribution of Bratton-Marshall-positive material in mice following intravenous injections of nitrosoureas.

Authors:  P Kari; W R McConnell; J M Finkel; D L Hill
Journal:  Cancer Chemother Pharmacol       Date:  1980       Impact factor: 3.333

5.  Treatment of malignant brain tumours with ACNU and phenobarbital: continuous infusion of ACNU into internal carotid artery and systemic administration of phenobarbital.

Authors:  K Yumitori; H Handa; T Teraura; J Yamashita
Journal:  Acta Neurochir (Wien)       Date:  1984       Impact factor: 2.216

6.  Studies on the mechanism of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)-induced hepatotoxicity. II. Biochemical and morphological characterization of the injury and its prevention by phenobarbital.

Authors:  A E Ahmed; M Grissom; R el-Azhary; A Haque; P J Boor; J Costanzi
Journal:  Cancer Chemother Pharmacol       Date:  1987       Impact factor: 3.333

7.  Relationship of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) pharmacokinetics of uptake, distribution, and tissue/plasma partitioning in rat organs and intracerebral tumors.

Authors:  V A Levin; P A Kabra; M A Freeman-Dove
Journal:  Cancer Chemother Pharmacol       Date:  1978       Impact factor: 3.333

8.  Metabolism and clearance of proxicromil--studies in rat, hamster, rabbit, dog, squirrel monkey, cynomolgus monkey, baboon and man.

Authors:  D A Smith; M G Neale
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1983 Jul-Sep       Impact factor: 2.441

9.  The hepatotoxicity of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) in rats. Ultrastructural evidence of a delayed microtubular toxicity.

Authors:  T Ducastelle; G Raguenez-Viotte; H Fouin-Fortunet; M Matysiak; J Hemet; J P Fillastre
Journal:  Cancer Chemother Pharmacol       Date:  1988       Impact factor: 3.333

10.  Chemopotentiation of CCNU metabolites by misonidazole.

Authors:  R T Mulcahy
Journal:  Br J Cancer       Date:  1985-05       Impact factor: 7.640
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.