Literature DB >> 4150789

Segmental aneuploidy and enzyme activity as a method for cytogenetic localization in drosophila melanogaster.

B R Stewart, J R Merriam.   

Abstract

A method of mapping genes which specify enzymes without the necessity of obtaining genetic variants has been explored. Three enzymes whose structural genes have known genetic positions were chosen to see if the relationship between gene dosage and enzyme activity could be used as a tool in cytological localization. Zw, the gene specifying G6PD, is located in the X chromosome region, 18D-18F. The structural gene for 6PGD, Pgd, maps in the X chromosome bands 2C1-2E1. Idh-NADP, the gene which specifies IDH-NADP, is found on the third chromosome, in bands 66B-67C.

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Year:  1974        PMID： 4150789      PMCID： PMC1213067     

Source DB:  PubMed          Journal:  Genetics        ISSN： 0016-6731            Impact factor:   4.562


  9 in total

1.  LEUCOCYTE ENZYMES IN DOWN'S SYNDROME.

Authors:  W J MELLMAN; F A OSKI; T A TEDESCO; A MACIERA-COELHO; H HARRIS
Journal:  Lancet       Date:  1964-09-26       Impact factor: 79.321

2.  Locating genetic loci with aneuploids.

Authors:  P S Carlson
Journal:  Mol Gen Genet       Date:  1972

3.  Genetic regulation of glucose 6-phosphate dehydrogenase activity in Drosophila melanogaster.

Authors:  M W Steele; W J Young; B Childs
Journal:  Biochem Genet       Date:  1969-08       Impact factor: 1.890

4.  Gene modulation in Drosophila: dosage compensation and relocated v + genes.

Authors:  J Tobler; J T Bowman; J R Simmons
Journal:  Biochem Genet       Date:  1971-04       Impact factor: 1.890

5.  Studies on the genetic control of tryptophan pyrrolase in Drosophila melanogaster.

Authors:  D L Baillie; A Chovnick
Journal:  Mol Gen Genet       Date:  1971

6.  X-linked electrophoretic variation in 6-phosphogluconate dehydrogenase in Drosophila melanogaster.

Authors:  W J Young
Journal:  J Hered       Date:  1966 Mar-Apr       Impact factor: 2.645

7.  GLUCOSE-6-PHOSPHATE DEHYDROGENASE IN DROSOPHILA: X-LINKED ELECTROPHORETIC VARIANTS.

Authors:  W J YOUNG; J E PORTER; B CHILDS
Journal:  Science       Date:  1964-01-10       Impact factor: 47.728

8.  Segmental aneuploidy and the genetic gross structure of the Drosophila genome.

Authors:  D L Lindsley; L Sandler; B S Baker; A T Carpenter; R E Denell; J C Hall; P A Jacobs; G L Miklos; B K Davis; R C Gethmann; R W Hardy; A H Steven; M Miller; H Nozawa; D M Parry; M Gould-Somero; M Gould-Somero
Journal:  Genetics       Date:  1972-05       Impact factor: 4.562

9.  Dosage compensation for enzyme activities in Drosophila melanogaster.

Authors:  R L Seecof; W D Kaplan; D G Futch
Journal:  Proc Natl Acad Sci U S A       Date:  1969-02       Impact factor: 11.205
  9 in total
  29 in total

1.  Developmental variation in effects of the second and third chromosomes on the activities of the glucose 6-phosphate and 6-phosphogluconate dehydrogenases in Drosophila melanogaster.

Authors:  N Miyashita; C C Laurie-Ahlberg
Journal:  Biochem Genet       Date:  1986-06       Impact factor: 1.890

2.  A sex-influenced modifier in Drosophila that affects a broad spectrum of target loci including the histone repeats.

Authors:  U Bhadra; M Pal-Bhadra; J A Birchler
Journal:  Genetics       Date:  1997-07       Impact factor: 4.562

3.  Quantitative analysis of X chromosome effects on the activities of the glucose 6-phosphate and 6-phosphogluconate dehydrogenases of Drosophila melanogaster.

Authors:  N Miyashita; C C Laurie-Ahlberg; A N Wilton; T H Emigh
Journal:  Genetics       Date:  1986-06       Impact factor: 4.562

4.  Control of drosopterin synthesis in Drosophila melanogaster: mutants showing an altered pattern of GTP cyclohydrolase activity during development.

Authors:  B A Evans; A J Howells
Journal:  Biochem Genet       Date:  1978-02       Impact factor: 1.890

5.  IN VIVO Function of Rare G6pd Variants from Natural Populations of DROSOPHILA MELANOGASTER.

Authors:  W F Eanes; J Hey
Journal:  Genetics       Date:  1986-07       Impact factor: 4.562

6.  Comparative properties of three forms of glucose-6-phosphate dehydrogenase in Drosophila melanogaster.

Authors:  J H Williamson; M M Bentley
Journal:  Biochem Genet       Date:  1983-12       Impact factor: 1.890

7.  Gene dosage effect for fumarate hydratase (FH; E.C. 4.2.1.2) in partial trisomy 1.

Authors:  R Braunger; H Kling; W Krone; M Schmid; J Olert
Journal:  Hum Genet       Date:  1977-08-31       Impact factor: 4.132

8.  Characterization of a low-activity allele of NADP+-dependent isocitrate dehydrogenase from Drosophila melanogaster.

Authors:  M M Bentley; R G Meidinger; J H Williamson
Journal:  Biochem Genet       Date:  1983-08       Impact factor: 1.890

9.  Genetic localization and sequential electrophoresis of glucose-6-phosphate dehydrogenase in Drosophila melanogaster.

Authors:  W F Eanes
Journal:  Biochem Genet       Date:  1983-08       Impact factor: 1.890

10.  gld-1, a tumor suppressor gene required for oocyte development in Caenorhabditis elegans.

Authors:  R Francis; M K Barton; J Kimble; T Schedl
Journal:  Genetics       Date:  1995-02       Impact factor: 4.562
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