Literature DB >> 4150768

Complementation studies of lethal alleles in the mouse causing deficiencies of glucose-6-phosphatase, tyrosine aminotransferase, and serine dehydratase.

S Gluecksohn-Waelsch, M B Schiffman, J Thorndike, C F Cori.   

Abstract

The pleiotropic effects of six radiation-induced lethal alleles at the albino locus in the mouse include deficiencies of various enzymes and of serum proteins. Closely correlated with the biochemical deficiencies are severe ultrastructural abnormalities of endoplasmic reticulum membranes and the Golgi apparatus in liver and kidney cells. Complementation studies led to the distinction of four different complementation groups among the six lethal alleles. The results are compatible with the interpretation that the six lethal alleles represent overlapping deletions of various sizes at and around the albino locus in the mouse, in a region concerned with the control of biochemical and structural differentiation.

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Year:  1974        PMID： 4150768      PMCID： PMC388107          DOI： 10.1073/pnas.71.3.825

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  7 in total

1.  The assay of aromatic amino acid transaminations and keto acid oxidation by the enol borate-tautomerase method.

Authors:  E C LIN; B M PITT; M CIVEN; W E KNOX
Journal:  J Biol Chem       Date:  1958-09       Impact factor: 5.157

2.  The developmental formation of liver glucose 6-phosphatase and reduced nicotinamide adenine dinucleotide phosphate dehydrogenase in fetal rats treated with thyroxine.

Authors:  O Greengard; H K Dewey
Journal:  J Biol Chem       Date:  1968-05-25       Impact factor: 5.157

3.  The quinacrine fluorescence karyotype of Mus musculus and demonstration of strain differences in secondary constrictions.

Authors:  V G Dev; M S Grewal; D A Miller; R E Kouri; J J Hutton; O J Miller
Journal:  Cytogenetics       Date:  1971

4.  Glucose-6-phosphatase deficiency caused by radiation-induced alleles at the albino locus in the mouse.

Authors:  R P Erickson; S Gluecksohn-Waelsch; C F Cori
Journal:  Proc Natl Acad Sci U S A       Date:  1968-02       Impact factor: 11.205

5.  Multiple biochemical effects of a series of x-ray induced mutations at the albino locus in the mouse.

Authors:  J Thorndike; M J Trigg; R Stockert; S Gluecksohn-Waelsch; C F Cori
Journal:  Biochem Genet       Date:  1973-05       Impact factor: 1.890

6.  Glucose 6-phosphatase deficiency: mechanisms of genetic control and biochemistry.

Authors:  S Gluecksohn-Waelsch; C F Cori
Journal:  Biochem Genet       Date:  1970-02       Impact factor: 1.890

7.  Ultrastructural basis of biochemical effects in a series of lethal alleles in the mouse. Neonatal and developmental studies.

Authors:  M J Trigg; S Gluecksohn-Waelsch
Journal:  J Cell Biol       Date:  1973-09       Impact factor: 10.539
  7 in total
  20 in total

Review 1.  Animal models of glycogen storage conditions. Their relation to human disease.

Authors:  S R Gross
Journal:  West J Med       Date:  1975-09

2.  Regulatory genes linked to the albino locus in the mouse confer competence for inducible expression on the structural gene encoding serine dehydratase.

Authors:  M Lia; D Bali; S Gluecksohn-Waelsch
Journal:  Proc Natl Acad Sci U S A       Date:  1992-03-15       Impact factor: 11.205

3.  Cytological observations of deletions in pachytene stages of oogenesis and spermatogenesis in the mouse.

Authors:  G Jagiello; J S Fang; H A Turchin; S E Lewis; S Gluecksohn-Waelsch
Journal:  Chromosoma       Date:  1976-11-29       Impact factor: 4.316

4.  The albino-deletion complex of the mouse: molecular mapping of deletion breakpoints that define regions necessary for development of the embryonic and extraembryonic ectoderm.

Authors:  S K Sharan; B Holdener-Kenny; S Ruppert; A Schedl; G Kelsey; E M Rinchik; T Magnuson
Journal:  Genetics       Date:  1991-11       Impact factor: 4.562

5.  Chemical and immunological studies of liver microsomes from mouse mutants with ultrastructurally abnormal hepatic endoplasmic reticulum.

Authors:  R P Erickson; P Siekevitz; K Jacobs; S Gluecksohn-Waelsch
Journal:  Biochem Genet       Date:  1974-07       Impact factor: 1.890

Review 6.  Glycogen storage diseases in animals and their potential value as models of human disease.

Authors:  H C Walvoort
Journal:  J Inherit Metab Dis       Date:  1983       Impact factor: 4.982

7.  Analysis of the albino-locus region of the mouse. III. Time of death of prenatal lethals.

Authors:  L B Russell; G D Raymer
Journal:  Genetics       Date:  1979-05       Impact factor: 4.562

8.  Complementation of gene deletions by cell hybridization.

Authors:  C F Cori; S Gluecksohn-Waelsch; H P Klinger; L Pick; S L Schlagman; L S Teicher; H F Wang-Chang
Journal:  Proc Natl Acad Sci U S A       Date:  1981-01       Impact factor: 11.205

9.  Nonhomologous pairing in mice heterozygous for a t haplotype can produce recombinant chromosomes with duplications and deletions.

Authors:  N Sarvetnick; H S Fox; E Mann; P E Mains; R W Elliott; L M Silver
Journal:  Genetics       Date:  1986-07       Impact factor: 4.562

10.  Mice homozygous for chromosomal deletions at the albino locus region lack specific polypeptides in two-dimensional gels.

Authors:  L J Baier; S M Hanash; R P Erickson
Journal:  Proc Natl Acad Sci U S A       Date:  1984-04       Impact factor: 11.205
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