Literature DB >> 4150680

Studies on the metabolism of ethynylestradiol in vitro and in vivo: the significance of 2-hydroxylation and the formation of polar products.

H M Bolt, H Kappus, H Remmer.   

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Year:  1973        PMID： 4150680     DOI： 10.3109/00498257309151602

Source DB:  PubMed          Journal:  Xenobiotica        ISSN： 0049-8254            Impact factor:   1.908


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  10 in total

Review 1.  The role of P-glycoprotein and organic anion-transporting polypeptides in drug interactions.

Authors:  Lawrence M DuBuske
Journal:  Drug Saf       Date:  2005       Impact factor: 5.606

2.  Metabolic oxidation of the ethynyl group in 4-ethynylbiphenyl.

Authors:  A Wade; A M Symons; L Martin; D V Parke
Journal:  Biochem J       Date:  1979-12-15       Impact factor: 3.857

3.  [Drug interactions in the use of steroid hormones, especially oral contraceptives].

Authors:  H M Bolt
Journal:  Arch Gynecol       Date:  1985

4.  Effect of rifampicin treatment on the metabolism of oestradiol and 17alpha-ethinyloestradiol by human liver microsomes.

Authors:  H M Bolt; H Kappus; M Bolt
Journal:  Eur J Clin Pharmacol       Date:  1975-06-13       Impact factor: 2.953

5.  The significance of covalent binding of catechols to proteins in vivo.

Authors:  H Remmer; M Scheulen; H Kappus; H M Bolt
Journal:  Arch Toxicol       Date:  1977-12-30       Impact factor: 5.153

6.  First pass biotransformation of ethinylestradiol in rat small intestine in situ.

Authors:  M Schwenk; C Schiemenz; V L del Pino; H Remmer
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1982-12       Impact factor: 3.000

7.  Identification of 17-alpha-ethynylestradiol-modified active site peptides and glutathione conjugates formed during metabolism and inactivation of P450s 2B1 and 2B6.

Authors:  Ute M Kent; Hsia-Lien Lin; Danielle E Mills; Kelly A Regal; Paul F Hollenberg
Journal:  Chem Res Toxicol       Date:  2006-02       Impact factor: 3.739

Review 8.  P450 enzymes. Inhibition mechanisms, genetic regulation and effects of liver disease.

Authors:  M Murray
Journal:  Clin Pharmacokinet       Date:  1992-08       Impact factor: 6.447

9.  Target organ-specific inactivation of drug metabolizing enzymes in kidney of hamsters treated with estradiol.

Authors:  D Roy; J G Liehr
Journal:  Mol Cell Biochem       Date:  1992-03-04       Impact factor: 3.396

10.  Interactions between clinically used drugs and oral contraceptives.

Authors:  H M Bolt
Journal:  Environ Health Perspect       Date:  1994-11       Impact factor: 9.031
  10 in total

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