Literature DB >> 4148725

Role of peroxide in phagocytic killing of pneumococci.

J Pitt, H P Bernheimer.   

Abstract

Two mutants of a pneumococcus type I with diminished peroxide production were selected from a population of nitrosoguanidine-treated cells. White cells of normal patients killed the mutant pneumococci as well as the otherwise isogenic wild-type strain. In patients studied with chronic granulomatous disease, however, the peroxide-poor strain was killed far less well than the wild type. These studies indicate that the removal of a peroxide-generating system in the phagocytic vacuole specifically brings forth the killing defect in chronic granulomatous disease.

Entities:  

Mesh：

Substances：

Year:  1974        PMID： 4148725      PMCID： PMC414763          DOI： 10.1128/iai.9.1.48-52.1974

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  11 in total

1.  Induction of closely linked multiple mutations by nitrosoguanidine.

Authors:  N Guerola; J L Ingraham; E Cerdá-Olmedo
Journal:  Nat New Biol       Date:  1971-03-24

2.  Improvement of leukocyte bactericidal activity in chronic granulomatous disease.

Authors:  R B Johnston; R L Baehner
Journal:  Blood       Date:  1970-03       Impact factor: 22.113

3.  Studies of polymorphonuclear leukocytes from patients with chronic granulomatous disease of childhood: bactericidal capacity for streptococci.

Authors:  E L Kaplan; T Laxdal; P G Quie
Journal:  Pediatrics       Date:  1968-03       Impact factor: 7.124

4.  Studies of the metabolic activity of leukocytes from patients with a genetic abnormality of phagocytic function.

Authors:  B Holmes; A R Page; R A Good
Journal:  J Clin Invest       Date:  1967-09       Impact factor: 14.808

5.  Leukocyte oxidase: defective activity in chronic granulomatous disease.

Authors:  R L Baehner; D G Nathan
Journal:  Science       Date:  1967-02-17       Impact factor: 47.728

6.  In vitro bactericidal capacity of human polymorphonuclear leukocytes: diminished activity in chronic granulomatous disease of childhood.

Authors:  P G Quie; J G White; B Holmes; R A Good
Journal:  J Clin Invest       Date:  1967-04       Impact factor: 14.808

7.  Leukocyte bactericidal activity in chronic granulomatous disease: correlation of bacterial hydrogen peroxide production and susceptibility to intracellular killing.

Authors:  G L Mandell; E W Hook
Journal:  J Bacteriol       Date:  1969-10       Impact factor: 3.490

8.  Correction of metabolic deficiencies in the leukocytes of patients with chronic granulomatous disease.

Authors:  R L Baehner; D G Nathan; M L Karnovsky
Journal:  J Clin Invest       Date:  1970-05       Impact factor: 14.808

9.  Deficiency of reduced nicotinamide-adenine dinucleotide oxidase in chronic granulomatous disease.

Authors:  R L Baehner; M L Karnovsky
Journal:  Science       Date:  1968-12-13       Impact factor: 47.728

10.  Interactions between rabbit polymorphonuclear leucocytes and staphylococci.

Authors:  Z A COHN; S I MORSE
Journal:  J Exp Med       Date:  1959-09-01       Impact factor: 14.307
View more
  14 in total

1.  E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection.

Authors:  David M Aronoff; Casey Lewis; Carlos H Serezani; Kathryn A Eaton; Deepti Goel; John C Phipps; Marc Peters-Golden; Peter Mancuso
Journal:  J Immunol       Date:  2009-07-27       Impact factor: 5.422

2.  Virulence of catalase-deficient aspergillus nidulans in p47(phox)-/- mice. Implications for fungal pathogenicity and host defense in chronic granulomatous disease.

Authors:  Y C Chang; B H Segal; S M Holland; G F Miller; K J Kwon-Chung
Journal:  J Clin Invest       Date:  1998-05-01       Impact factor: 14.808

3.  Anaerobic phagocytosis, killing, and degradation of Streptococcus pneumoniae by human peripheral blood leukocytes.

Authors:  M Thore; S Löfgren; A Tärnvik; T Monsen; E Selstam; L G Burman
Journal:  Infect Immun       Date:  1985-01       Impact factor: 3.441

Review 4.  How neutrophils kill microbes.

Authors:  Anthony W Segal
Journal:  Annu Rev Immunol       Date:  2005       Impact factor: 28.527

5.  Extracellular stimulation by serum proteins required for maximal intracellular killing of microorganisms by mouse peritoneal macrophages.

Authors:  P C Leijh; T L van Zwet; R van Furth
Journal:  Infect Immun       Date:  1984-12       Impact factor: 3.441

6.  Intrapulmonary administration of leukotriene B4 enhances pulmonary host defense against pneumococcal pneumonia.

Authors:  Peter Mancuso; Casey Lewis; Carlos Henrique Serezani; Deepti Goel; Marc Peters-Golden
Journal:  Infect Immun       Date:  2010-03-15       Impact factor: 3.441

7.  Reactive oxygen species regulate neutrophil recruitment and survival in pneumococcal pneumonia.

Authors:  Helen M Marriott; Laura E Jackson; Thomas S Wilkinson; A John Simpson; Tim J Mitchell; David J Buttle; Simon S Cross; Paul G Ince; Paul G Hellewell; Moira K B Whyte; David H Dockrell
Journal:  Am J Respir Crit Care Med       Date:  2008-01-17       Impact factor: 21.405

Review 8.  The function of the NADPH oxidase of phagocytes and its relationship to other NOXs in plants, invertebrates, and mammals.

Authors:  Anthony W Segal
Journal:  Int J Biochem Cell Biol       Date:  2007-10-09       Impact factor: 5.085

9.  Lipid peroxidation in the killing of phagocytized pneumococci.

Authors:  S B Shohet; J Pitt; R L Baehner; D G Poplack
Journal:  Infect Immun       Date:  1974-12       Impact factor: 3.441

Review 10.  The NADPH oxidase of professional phagocytes--prototype of the NOX electron transport chain systems.

Authors:  Andrew R Cross; Anthony W Segal
Journal:  Biochim Biophys Acta       Date:  2004-06-28
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.