Literature DB >> 4148703

Guanylate cyclase: inhibition by light in retinal photoreceptors.

R E Bensinger, R T Fletcher, G J Chader.   

Abstract

Guanylate cyclase activity of retinal rod outer segments was measured by an assay procedure that minimizes the technical problems caused by the high activity of cyclic nucleotide phosphodiesterase in neural tissue. Cyclase activity in rods is significantly higher than in brain. Moreover, activity is two-fold higher in dark-adapted rods than in light-bleached rods, a sensitivity that is lost when the preparation is treated with detergent.

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Year:  1974        PMID： 4148703     DOI： 10.1126/science.183.4120.86

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  6 in total

1.  Nucleotide regulation of heat-stable enterotoxin receptor binding and of guanylate cyclase activation.

Authors:  L C Katwa; C D Parker; J K Dybing; A A White
Journal:  Biochem J       Date:  1992-05-01       Impact factor: 3.857

2.  Light-stimulated phosphorylation of rhodopsin in the retina: the presence of a protein kinase that is specific for photobleached rhodopsin.

Authors:  M Weller; N Virmaux; P Mandel
Journal:  Proc Natl Acad Sci U S A       Date:  1975-01       Impact factor: 11.205

3.  Light-activated hydrolysis of GTP and cyclic GMP in the rod outer segments.

Authors:  E Bignetti; A Cavaggioni; R T Sorbi
Journal:  J Physiol       Date:  1978-06       Impact factor: 5.182

4.  Intracellular biochemical manipulation of phototransduction in detached rod outer segments.

Authors:  W A Sather; P B Detwiler
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

5.  Guanosine 3',5'-cyclic monophosphate and the in vitro physiology of frog photoreceptor membranes.

Authors:  M L Woodruff; D Bownds; S H Green; J L Morrisey; A Shedlovsky
Journal:  J Gen Physiol       Date:  1977-05       Impact factor: 4.086

6.  Regulation of guanylate cyclase in guinea-pig islets of Langerhans.

Authors:  S L Howell; W Montague
Journal:  Biochem J       Date:  1974-08       Impact factor: 3.857
  6 in total

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